N-[(tert-Butoxy)carbonyl]-N-methylglycyl-N-methylglycine

Base Information

• Chemical Name: N-[(tert-Butoxy)carbonyl]-N-methylglycyl-N-methylglycine
• CAS No.: 56612-14-7
• Molecular Formula: C11H20N2O5
• Molecular Weight: 260.28700
• Hs Code.: 2924199090
• Mol file: 56612-14-7.mol

Synonyms:N-[N-(tert-butoxycarbonyl)-N-methylglycyl]-N-methylglycine;2-[[2-[tert-butoxycarbonyl(methyl)amino]acetyl]-methyl-amino]acet ic acid;N-(N-Boc-N-methylglycyl)-N-methylglycine;Boc-Sar-Sar-OH;

Chemical Property of N-[(tert-Butoxy)carbonyl]-N-methylglycyl-N-methylglycine

Chemical Property:

• Boiling Point: 403.8±38.0 °C(Predicted)
• PKA: 3.44±0.10(Predicted)
• PSA: 87.15000
• Density: 1.183
• LogP: 0.39630
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

{[2-(tert-Butoxycarbonyl-methyl-amino)-acetyl]-methyl-amino}-aceticacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[(tert-Butoxy)carbonyl]-N-methylglycyl-N-methylglycine

There total 4 articles about N-[(tert-Butoxy)carbonyl]-N-methylglycyl-N-methylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Boc-sarcosyl-sarcosine ethyl ester (77615-34-0) → Boc-Sar-Sar (56612-14-7)

Guidance literature:

Boc-sarcosyl-sarcosine ethyl ester; With water; lithium hydroxide; In tetrahydrofuran;

With hydrogenchloride; In water; pH=3;

Reference yield:

N-(tert-butoxycarbonyl)sarcosine (13734-36-6) → Boc-Sar-Sar (56612-14-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC

2: aq. NaOH / methanol

With sodium hydroxide; dicyclohexyl-carbodiimide; In methanol;

Reference yield:

methyl 2-[[2-[tert-butoxycarbonyl(methyl)amino]acetyl]methylamino]acetate (42492-58-0) → Boc-Sar-Sar (56612-14-7)

Guidance literature:

With sodium hydroxide; In methanol;

upstream raw materials:

methyl 2-[[2-[tert-butoxycarbonyl(methyl)amino]acetyl]methylamino]acetate

N-(tert-butyloxycarbonyl) azide

N-(tert-butoxycarbonyl)sarcosine

Boc-sarcosyl-sarcosine ethyl ester