(S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide

Base Information

Chemical Name:(S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide
CAS No.:566200-79-1
Molecular Formula:C37H33N3O3
Molecular Weight:567.687
Hs Code.:
Mol file:566200-79-1.mol

Synonyms:6-[(1S)-1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide;Benzoic acid,6-(((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)imino)methyl)-2,3-dimethoxy-,ethyl ester;6-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-methyl]-2,3-dimethoxy-benzoic acid ethyl ester;ETHYL 6-[(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)IMINOMETHYL]-2,3-DIMETHOXY-BENZOATE;6-[(1-{2-[(2-methyl-5-quinolinyl)oxy]ethyl}-4-piperidinyl)methyl]-2H-1,4-benzoxazin-3(4H)-one;

Suppliers and Price of (S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
(S)-6-(1,3-Dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl)-N-methyl-2-naphthamide 95%+
1g
$ 2336.00

Chemenu
(S)-6-(1,3-Dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl)-N-methyl-2-naphthamide 95%+
250mg
$ 1251.00

Chemenu
(S)-6-(1,3-Dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl)-N-methyl-2-naphthamide 95%+
100mg
$ 651.00

Total 6 raw suppliers

Chemical Property of (S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide

Chemical Property:

PSA：87.38000
LogP:6.24530

Purity/Quality:

NLT 98% ^*data from raw suppliers

(S)-6-(1,3-Dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl)-N-methyl-2-naphthamide 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide

There total 2 articles about (S)-6-(1,3-dihydroxy-1-(1-trityl-1H-iMidazol-4-yl)propyl)-N-Methyl-2-naphthaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 566200-78-0
ethyl (3S)-3-hydroxy-3-{6-[(methylamino)carbonyl]-2-naphthyl)-3-(1-trityl-1H-imidazol-4-yl)propanoate

: 566200-79-1
6-[(1S)-1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide

Guidance literature:: ethyl (3S)-3-hydroxy-3-{6-[(methylamino)carbonyl]-2-naphthyl)-3-(1-trityl-1H-imidazol-4-yl)propanoate; With sodium tetrahydroborate; calcium chloride; In tetrahydrofuran; ethanol; at -7 - 5 ℃; for 8.5h;

With hydrogenchloride; water; In tetrahydrofuran; ethanol; ethyl acetate; at 5 ℃;

Reference yield: 90.0%

: ethyl (3S)-3-hydroxy-3-{6-[(methylamino)carbonyl]-2-naphthyl}-3-(1-trityl-1H-imidazol-4-yl)propanoate

: 566200-79-1
6-[(1S)-1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide

Guidance literature:: With sodium tetrahydroborate; calcium chloride; In tetrahydrofuran; ethanol; at 0 - 5 ℃; for 0.5h;

ethyl (3S)-3-hydroxy-3-{6-[(methylamino)carbonyl]-2-naphthyl}-3-(1-trityl-1H-imidazol-4-yl)propanoate; In tetrahydrofuran; ethanol; at 0 - 20 ℃; for 5h;

With hydrogenchloride; In tetrahydrofuran; ethanol; water; at 35 ℃;

Reference yield: 62.0%

: 566200-79-1
6-[(1S)-1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide

: 426219-18-3,426219-23-0,426219-32-1
orteronel

Guidance literature:: 6-[(1S)-1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide; With methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 - 5 ℃; for 0.666667h;

In tetrahydrofuran; methanol; acetonitrile; at 60 - 65 ℃; for 4h;

With hydrogenchloride; sodium hydroxide; ammonium chloride; In tetrahydrofuran; methanol; water; acetonitrile; at 0 - 5 ℃; pH=8;