Kasugamycin hydrochloride

Base Information

• Chemical Name: Kasugamycin hydrochloride
• CAS No.: 19408-46-9
• Deprecated CAS: 11014-57-6,12609-82-4,39080-40-5,1135443-65-0,1135443-65-0,12609-82-4
• Molecular Formula: C14H26ClN3O9
• Molecular Weight: 415.88
• European Community (EC) Number: 606-307-1,615-014-8
• UNII: SXA18D440T
• DSSTox Substance ID: DTXSID2040739
• Wikipedia: Kasugamycin
• Wikidata: Q27289442
• ChEMBL ID: CHEMBL3186853
• Mol file: 19408-46-9.mol

Synonyms:3-O-(2-amino-4((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-alpha-D-arabino-hexopyranosyl)-D-chiroinositol;kasugamycin;kasugamycin hydrochloride;kasugamycin hydrochloride monohydrate;kasugamycin monohydrochloride;kasugamycin, phosphate salt;kasugamycin, sulfate salt

Chemical Property of Kasugamycin hydrochloride

Chemical Property:

• Vapor Pressure: 2.04E-18mmHg at 25°C
• Melting Point: 203oC (dec)
• Refractive Index: 1.738
• Boiling Point: 604.4 °C at 760 mmHg
• PKA: 3.23 (carboxyl), 7.73 and 11.0 (bases)
• Flash Point: 319.3 °C
• PSA: 218.81000
• Density: 1.97g/cm3
• LogP: -2.33510
• Storage Temp.: 2-8°C
• Solubility.: H2O: soluble
• Water Solubility.: 125 g l-1 (25 °C)
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 415.1357571
• Heavy Atom Count: 27
• Complexity: 532

Purity/Quality:

99% ^*data from raw suppliers

Kasugamycin HCl ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Pesticides -> Fungicides
• Canonical SMILES: CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N.Cl
• Isomeric SMILES: C[C@@H]1[C@H](C[C@@H]([C@H](O1)OC2[C@@H]([C@H](C([C@@H]([C@@H]2O)O)O)O)O)N)N=C(C(=O)O)N.Cl
• Description: Kasugamycin is an aminoglycosidic antibiotic isolated from S. kasugaensis. It blocks the initiation of translation, preventing initiation complex formation on 30S ribosomes in bacteria.
• Uses: antifungal kasugamycin, derived from Streptomyces kasuguensis, is also used to control rice blast.It acts by inhibiting protein synthesis by interfering with the binding of aminoacyl-tRNA to the mRNA-30s ribosomal subunit complex (Yamaguchi, 1998). Kasugamycin Hydrochloride is an aminoglycoside antibiotic that inhibits the initiation of translation. It is also a type of fungicide that controls leaf and neck blast disease caused by Pyricularia oryzae and increases rice yields.