2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester

Base Information

• Chemical Name: 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester
• CAS No.: 56687-67-3
• Molecular Formula: C21H38O2
• Molecular Weight: 322.53
• Mol file: 56687-67-3.mol

Synonyms:2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester

Chemical Property of 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester

Chemical Property:

• Boiling Point: 376.7±10.0 °C(Predicted)
• PSA: 26.30000
• Density: 0.938±0.06 g/cm3(Predicted)
• LogP: 6.13270

Purity/Quality:

99% ^*data from raw suppliers

DCPLA-ME >98.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester

There total 3 articles about 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

diiodomethane (75-11-6) + Methyl linoleate (112-63-0) → 8-[2-(2-pentylcyclopropylmethyl)cyclopropyl]octanoic acid methyl ester (56687-67-3)

Guidance literature:

Methyl linoleate; With diethylzinc; In hexane; dichloromethane; at -5 - 0 ℃; for 1h; Inert atmosphere;

diiodomethane; In hexane; dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2014.11.025

Reference yield:

Methyl linoleate (112-63-0) + Chloroiodomethane (593-71-5) → 8-[2-(2-pentylcyclopropylmethyl)cyclopropyl]octanoic acid methyl ester (56687-67-3)

Guidance literature:

With diethylzinc; In hexane; dichloromethane; at -5 - 20 ℃; for 3h; Inert atmosphere;

Reference yield:

→ 8-[2-(2-pentylcyclopropylmethyl)cyclopropyl]octanoic acid methyl ester (56687-67-3)

Guidance literature:

trans, trans-Linolensaeuremethylester, Zn, Cu(Ac)2*H2O, (ICH2)2;

DOI:10.1007/BF02531869

upstream raw materials:

diiodomethane

Methyl linoleate

Chloroiodomethane

Refernces

• 1、 Ann, Jihyae,Yoon, Suyoung,Baek, Jisoo,Kim, Da Hye,Lewin, Nancy E.,Hill, Colin S.,Blumberg, Peter M.,Lee, Jeewoo. "Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones)". . p. 332 - 341. Retrieved 2015/05/04.