1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-8-phenyl-, (8S)-

Base Information

• Chemical Name: 1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-8-phenyl-, (8S)-
• CAS No.: 85559-65-5
• Molecular Formula: C30H40 N4 O3
• Molecular Weight: 504.673
• Mol file: 85559-65-5.mol

Synonyms:1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-(1-oxo-3-phenyl-2-propenyl)-8-phenyl-, [S-(E)]-;1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propenyl]-8-phenyl-, (8S)- (9CI);Verbascenin; Verbascenine

Chemical Property of 1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-8-phenyl-, (8S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-8-phenyl-, (8S)-

There total 4 articles about 1,5,9,13-Tetraazacycloheptadecan-6-one,13-acetyl-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-8-phenyl-, (8S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-(S)-isoverbamethine (162709-45-7) → verbascenine (85559-65-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 10percent HCl, NH₂OH*HCl / H₂O / 1 h / 90 °C

2: 50 percent / ethanol; H₂O / 16 h / Irradiation

3: CHCl₃ / Ambient temperature

With hydrogenchloride; hydroxylamine hydrochloride; In ethanol; chloroform; water;

DOI:10.1016/0040-4039(94)02317-5

Reference yield:

(-)-verballocine (164176-10-7) → verbascenine (85559-65-5)

Guidance literature:

Multi-step reaction with 4 steps

2: ethanol; H₂O / 16 h / Irradiation

3: 10percent HCl, NH₂OH*HCl / H₂O / 1 h / 90 °C

4: CHCl₃ / Ambient temperature

With hydrogenchloride; hydroxylamine hydrochloride; In ethanol; chloroform; water;

DOI:10.1016/0040-4039(94)02317-5

Reference yield:

(+)-(S)-2-phenyl-9-[(E)-phenylprop-2-enoyl]-1,5,9,14-tetraazabicyclo[12.3.1]octadecan-4-one (162465-73-8) → verbascenine (85559-65-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 10percent HCl, NH₂OH*HCl / H₂O / 1 h / 90 °C

2: CHCl₃ / Ambient temperature

With hydrogenchloride; hydroxylamine hydrochloride; In chloroform; water;

DOI:10.1016/0040-4039(94)02317-5

upstream raw materials:

acetic anhydride

(-)-(S)-8-phenyl-1-[(E)-phenylprop-2-enoyl]-1,5,9,13-tetraazacycloheptadecan-6-one

(-)-verballocine

(+)-(S)-isoverbamethine

Downstream raw materials:

N,N',N''-Triacetylspermidin

N,N',N'',N'''-Tetraacetylspermin

9-Acetylverbascenin

7',8'-Dihydroverbascenin