[(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol

Base Information

Chemical Name:[(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol
CAS No.:118237-86-8
Molecular Formula:C₁₁H₁₄ClN₅O
Molecular Weight:267.718
Hs Code.:
Mol file:118237-86-8.mol

Synonyms:Cyclopentanemethanol,3-(2-amino-6-chloro-9H-purin-9-yl)-, cis-(?à)-; NSC 615812

Suppliers and Price of [(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of [(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol

Chemical Property:

Vapor Pressure:2.37E-13mmHg at 25°C
Boiling Point:559.4°Cat760mmHg
Flash Point:292.1°C
Density:1.75g/cm³

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol

There total 6 articles about [(1R,3S)-3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 122624-78-6
(+/-)-cis-<3-<(2,5-diamino-6-chloro-4-pyrimidinyl)amino>cyclopentyl>carbinol

: 122-51-0
orthoformic acid triethyl ester

: 118237-86-8,2022943-79-7
(+/-)-cis-<3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl>carbinol

Guidance literature:: With hydrogenchloride; overnight;
DOI:10.1021/jm00163a004

Reference yield:

: 61865-50-7,86252-77-9
Acetic acid 4-acetylamino-cyclopent-2-enylmethyl ester

: 118237-86-8,2022943-79-7
(+/-)-cis-<3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl>carbinol

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / 10percent Pd/C / ethanol

2: 0.5 N aq. barium hydroxide / Heating; overnight

3: Et₃N / butan-1-ol / 48 h / Heating

4: 1.) 3 N HCl, sodium nitrite, 2.) sodium acetate trihydrate / 1.) water, 2.) acetic acid, water, RT, overnight

5: 69 percent / Zn, acetic acid / H₂O; ethanol / 3 h / Heating

6: 73 percent / 12 N HCl / overnight

With hydrogenchloride; barium dihydroxide; hydrogen; sodium acetate; acetic acid; triethylamine; zinc; sodium nitrite; palladium on activated charcoal; In ethanol; water; butan-1-ol;
DOI:10.1021/jm00163a004

Reference yield:

: 123288-54-0,1110772-11-6
3-aminocyclopentyl-1-methanol

: 118237-86-8,2022943-79-7
(+/-)-cis-<3-(2-amino-6-chloro-9H-purin-9-yl)cyclopentyl>carbinol

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / butan-1-ol / 48 h / Heating

2: 1.) 3 N HCl, sodium nitrite, 2.) sodium acetate trihydrate / 1.) water, 2.) acetic acid, water, RT, overnight

3: 69 percent / Zn, acetic acid / H₂O; ethanol / 3 h / Heating

4: 73 percent / 12 N HCl / overnight

With hydrogenchloride; sodium acetate; acetic acid; triethylamine; zinc; sodium nitrite; In ethanol; water; butan-1-ol;
DOI:10.1021/jm00163a004