1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-

Base Information

Chemical Name:1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-
CAS No.:87540-37-2
Molecular Formula:C21H22 Cl N5 O2
Molecular Weight:411.8847
Hs Code.:
DSSTox Substance ID:DTXSID10236414
Wikidata:Q83118368
ChEMBL ID:CHEMBL13909

Synonyms:BRN 6444445;1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-;N,N-Bis(2-methoxyethyl)-3-(3-chlorophenyl)-1,2,4-triazolo(3,4-a)phthalazin-6-amine;87540-37-2;CHEMBL13909;DTXSID10236414;LS-156545

Suppliers and Price of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-

Chemical Property:

Density:1.31g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:411.1462027
Heavy Atom Count:29
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCCN(CCOC)C1=NN2C(=NN=C2C3=CC=CC=C31)C4=CC(=CC=C4)Cl

Technology Process of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)-

There total 3 articles about 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N,N-bis(2-methoxyethyl)-3-(3-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 111-95-5
Bis-(2-methoxyethyl)amine

: 87539-81-9
6-Chloro-3-(3-chloro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazine

: 87540-37-2
[3-(3-Chloro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]-bis-(2-methoxy-ethyl)-amine

Guidance literature:: at 140 ℃; for 30h;
DOI:10.1021/jm00401a010

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87540-37-2
[3-(3-Chloro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]-bis-(2-methoxy-ethyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / Et₃N / dioxane / 5 h / Heating

2: 78 percent / 30 h / 140 °C

With triethylamine; In 1,4-dioxane;
DOI:10.1021/jm00401a010

Reference yield:

: 618-46-2
m-Chlorobenzoyl chloride

: 87540-37-2
[3-(3-Chloro-phenyl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl]-bis-(2-methoxy-ethyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / Et₃N / dioxane / 5 h / Heating

2: 78 percent / 30 h / 140 °C

With triethylamine; In 1,4-dioxane;
DOI:10.1021/jm00401a010