Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-

Base Information

Chemical Name:Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-
CAS No.:122224-84-4
Molecular Formula:C38H58 N6 O9
Molecular Weight:742.913
Hs Code.:
UNII:4DEV5X6A19
Pharos Ligand ID:8A5V7931782D
ChEMBL ID:CHEMBL58263
Mol file:122224-84-4.mol

Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-

Synonyms:2-benzyl-3-((2-methoxyethoxymethoxyethyl)methylaminocarbonyl)propionyl-L-histidine-3-ethyl-5-(1'-hydroxy-2'-amino-3'-cyclohexylpropyl)oxazolidin-2-one amide;A 65317;A-65317

Suppliers and Price of Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
A 65317 95.00%
5MG
$ 497.68

Total 1 raw suppliers

Chemical Property of Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1024°Cat760mmHg
Flash Point:573.1°C
PSA：191.63000
Density:1.209g/cm³
LogP:4.05680
XLogP3:2.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:23
Exact Mass:742.42652745
Heavy Atom Count:53
Complexity:1120

Purity/Quality:

97% ^*data from raw suppliers

A 65317 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CC(OC1=O)C(C(CC2CCCCC2)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC4=CC=CC=C4)CC(=O)N(C)CCOCOCCOC)O
Isomeric SMILES:CCN1C[C@H](OC1=O)[C@@H]([C@H](CC2CCCCC2)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CC4=CC=CC=C4)CC(=O)N(C)CCOCOCCOC)O

Technology Process of Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)-

There total 7 articles about Butanediamide, N1-((1S)-2-(((1S,2R)-1-(cyclohexylmethyl)-2-((5S)-3-ethyl-2-oxo-5-oxazolidinyl)-2-hydroxyethyl)amino)-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl)-N4-(2-((2-methoxyethoxy)methoxy)ethyl)-N4-methyl-2-(phenylmethyl)-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17791-52-5
(S)-2-tert-Butoxycarbonylamino-3-(3H-imidazol-4-yl)-propionic acid

: 122224-84-4
A-65317

Guidance literature:: Multi-step reaction with 3 steps

1: 1-hydroxybenzotriazole, N-methylmorpholine, 1-ethyl-3-<(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 1.) -23 deg C, 2 h, 2.) RT, 16 h

2: ethanolic HCl / 1 h

3: 1-hydroxybenzotriazole, N-methylmorpholine, 1-ethyl-3-<(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 1.) -23 deg C, 2 h, 2.) RT, 16 h

With 4-methyl-morpholine; hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00169a024

Reference yield:

: 119589-20-7
1-<(methoxyethoxy)methoxy>-2-(methylamino)ethane

: 122224-84-4
A-65317

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N-methylmorpholine, isobutyl chloroformate / 1.) CH₂Cl₂, -10 deg C, 3 min, 2a.) -10 deg, 15 min, 2b.) RT, 2 h

2: 100 percent / H₂ / 10percent Pd/C / methanol / 1 h

3: 1-hydroxybenzotriazole, N-methylmorpholine, 1-ethyl-3-<(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 1.) -23 deg C, 2 h, 2.) RT, 16 h

With 4-methyl-morpholine; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; isobutyl chloroformate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a024

Reference yield:

: 119589-19-4
2-<<(benzyloxy)carbonyl>methylamino>-1-<(methoxyethoxy)methoxy>ethane

: 122224-84-4
A-65317

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / H₂ / 10percent Pd/C / methanol / 12 h

2: 1.) N-methylmorpholine, isobutyl chloroformate / 1.) CH₂Cl₂, -10 deg C, 3 min, 2a.) -10 deg, 15 min, 2b.) RT, 2 h

3: 100 percent / H₂ / 10percent Pd/C / methanol / 1 h

4: 1-hydroxybenzotriazole, N-methylmorpholine, 1-ethyl-3-<(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 1.) -23 deg C, 2 h, 2.) RT, 16 h

With 4-methyl-morpholine; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; isobutyl chloroformate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a024