(2-Bromo-4-fluorophenyl)hydrazine hydrochloride

Base Information

Chemical Name:(2-Bromo-4-fluorophenyl)hydrazine hydrochloride
CAS No.:571170-91-7
Molecular Formula:C6H6BrFN2.ClH
Molecular Weight:241.49
Hs Code.:2928000090
European Community (EC) Number:818-197-4
DSSTox Substance ID:DTXSID60585868
Mol file:571170-91-7.mol

Synonyms:(2-bromo-4-fluorophenyl)hydrazine hydrochloride;571170-91-7;(2-Bromo-4-fluorophenyl)hydrazine, HCl;(2-BROMO-4-FLUOROPHENYL)HYDRAZINE HCL;(2-bromo-4-fluorophenyl)hydrazine;hydrochloride;DTXSID60585868;WXA17091;2-Bromo-4-fluorophenylhydrazine hcl;MFCD08448703;AKOS027254675;AS-39199;CS-0242932;(2-bromo-4-fluorophenyl)hydrazinehydrochloride;EN300-25696;J-508300;Z216309312;(2-Bromo-4-fluorophenyl)hydrazine--hydrogen chloride (1/1)

Suppliers and Price of (2-Bromo-4-fluorophenyl)hydrazine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2-Bromo-4-fluorophenyl)hydrazinehydrochloride 95+%
1g
$ 564.00

American Custom Chemicals Corporation
(2-BROMO-4-FLUOROPHENYL)HYDRAZINE HYDROCHLORIDE 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
(2-BROMO-4-FLUOROPHENYL)HYDRAZINE HYDROCHLORIDE 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
(2-BROMO-4-FLUOROPHENYL)HYDRAZINE HYDROCHLORIDE 95.00%
1G
$ 983.52

Total 2 raw suppliers

Chemical Property of (2-Bromo-4-fluorophenyl)hydrazine hydrochloride

Chemical Property:

PSA：38.05000
LogP:3.44910
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:239.94652
Heavy Atom Count:11
Complexity:112

Purity/Quality:

99% ^*data from raw suppliers

(2-Bromo-4-fluorophenyl)hydrazinehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)Br)NN.Cl

Technology Process of (2-Bromo-4-fluorophenyl)hydrazine hydrochloride

There total 1 articles about (2-Bromo-4-fluorophenyl)hydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1003-98-1
2-bromo-4-fluoroaniline

: 571170-91-7
(2-bromo-4-fluorophenyl)hydrazine hydrochloride

Guidance literature:: 2-bromo-4-fluoroaniline; With hydrogenchloride; sodium nitrite; at -4 ℃;

With hydrogenchloride; tin(ll) chloride; at 0 - 5 ℃;
DOI:10.1016/j.bmcl.2010.10.018

Reference yield:

: 617-35-6
2-oxo-propionic acid ethyl ester

: 571170-91-7
(2-bromo-4-fluorophenyl)hydrazine hydrochloride

: 1412398-37-8
(E)-ethyl 2-(2-(2-bromo-4-fluorophenyl)hydrazono)propanoate

Guidance literature:: With toluene-4-sulfonic acid; In toluene; for 2h; Reflux;

Reference yield:

: 571170-91-7
(2-bromo-4-fluorophenyl)hydrazine hydrochloride

: [(1R)-9-[(1R)-1-(4-chlorophenyl)-2-fluoroethyl]-6-fluoro-8-(methylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl]acetic acid

Guidance literature:: Multi-step reaction with 11 steps

1.1: acetic acid / water / 16 h / Heating / reflux

2.1: copper(l) iodide / dimethyl sulfoxide / 24.08 h / 100 °C

2.2: 0.5 h

3.1: Resolution of racemate

4.1: di-tert-butyl-diazodicarboxylate; triphenylphosphine / tetrahydrofuran / 2.17 h / 20 °C

5.1: lithium hydroxide; water / tetrahydrofuran; methanol / 2 h / 20 °C

6.1: hydrogen / palladium 10% on activated carbon / 24.08 h / 20 °C

7.1: di-tert-butyl-diazodicarboxylate; triphenylphosphine / tetrahydrofuran / 1.33 h / 20 °C

8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C

9.1: triethylamine / dichloromethane / 0.5 h / 0 °C

10.1: triethylamine tris(hydrogen fluoride) / 0.08 h / 200 °C

11.1: lithium hydroxide; water / tetrahydrofuran; methanol / 16 h / 0 °C

With lithium hydroxide; copper(l) iodide; di-tert-butyl-diazodicarboxylate; tetrabutyl ammonium fluoride; water; hydrogen; acetic acid; triethylamine tris(hydrogen fluoride); triethylamine; triphenylphosphine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; 1.1: Fischer Indole Synthesis / 4.1: Mitsunobu reaction / 7.1: Mitsunobu reaction;