6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

Base Information

Chemical Name:6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
CAS No.:571189-64-5
Molecular Formula:C15H18N4O2
Molecular Weight:286.32900
Hs Code.:
Mol file:571189-64-5.mol

Synonyms:6-Acetyl-2-amino-8-cyclopentyl-5-methyl-8H-pyrido [2,3-d]pyrimidin-7-one;6-Acetyl-2-amino-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one;6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one;

Suppliers and Price of 6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of 6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

Chemical Property:

Melting Point:None °C
Boiling Point:531.7±60.0 °C(Predicted)
PKA:3.70±0.20(Predicted)
PSA：90.87000
Density:1.329±0.06 g/cm3(Predicted)
LogP:2.58100

Purity/Quality:: NLT 98% ^*data from raw suppliers

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Technology Process of 6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

There total 2 articles about 6-acetyl-2-aMino-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

: 571190-15-3
8-cyclopentyl-6-(1-ethoxyvinyl)-2-(4-methoxybenzylamino)-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

: 571189-64-5
6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

Guidance literature:: In dichloromethane; trifluoroacetic acid;

Reference yield:

: 571190-14-2
6-bromo-8-cyclopentyl-2-(4-methoxybenzylamino)-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

: 571189-64-5
6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine)palladium⁽⁰⁾ / toluene / 3 h / Heating

2: 0.040 g / TFA / 5 h / Heating

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; trifluoroacetic acid; In toluene; 1: Stille coupling;
DOI:10.1021/jm049354h