4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one

Base Information

Chemical Name:4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one
CAS No.:2498-43-3
Molecular Formula:C₉H₁₃IN₃O₇P
Molecular Weight:433.096
Hs Code.:
Mol file:2498-43-3.mol

Synonyms:Cytidine,2'-deoxy-5-iodo-, 5'-(dihydrogen phosphate) (8CI); Cytidine, 2'-deoxy-5-iodo-,5'-phosphate (7CI); 5-Iododeoxycytidine monophosphate

Suppliers and Price of 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one

Chemical Property:

Vapor Pressure:1.2E-19mmHg at 25°C
Boiling Point:650°Cat760mmHg
Flash Point:346.9°C
Density:2.54g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one

There total 2 articles about 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5-iodopyrimidin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1032-65-1,25609-92-1
cytidine 5'-(dihydrogen phosphate)

: 2498-43-3
5-iodo-2'-deoxycytidine 5'-monophosphate

Guidance literature:: With iodic acid;
DOI:10.1080/15257770.2011.595379

Reference yield:

: 2498-43-3
5-iodo-2'-deoxycytidine 5'-monophosphate

Guidance literature:: 2'-Desoxy-cytidin-5'-phosphat, I2, HIO3, Eg.;
DOI:10.1021/jm00340a019

Reference yield:

: 2498-43-3
5-iodo-2'-deoxycytidine 5'-monophosphate

: 1219116-75-2
C₂₀H₂₀N₇O₁₁PS

Guidance literature:: Multi-step reaction with 2 steps

1: trisodium tris(3-sulfophenyl)phosphine; palladium diacetate; caesium carbonate / water; acetonitrile / 1 h / 100 °C / Inert atmosphere

2: aniline; ammonium acetate; acetic acid / water / 24 h / 20 °C / pH 4.5 / Inert atmosphere

With ammonium acetate; trisodium tris(3-sulfophenyl)phosphine; palladium diacetate; caesium carbonate; acetic acid; aniline; In water; acetonitrile; 1: |Suzuki Coupling;
DOI:10.1002/cplu.201200056