4-(benzyloxy)-3-methoxybenzoic anhydride

Base Information

• Chemical Name: 4-(benzyloxy)-3-methoxybenzoic anhydride
• CAS No.: 1592-47-8
• Molecular Formula: C30H26 O7
• Molecular Weight: 498.532
• Mol file: 1592-47-8.mol

Synonyms:Benzoicacid, 3-methoxy-4-(phenylmethoxy)-, anhydride (9CI); Benzoic acid,4-(benzyloxy)-3-methoxy-, anhydride (6CI); Benzoic anhydride,4,4'-bis(benzyloxy)-3,3'-dimethoxy- (3CI); 4-(Benzyloxy)-3-methoxybenzoicanhydride; NSC 16756

Chemical Property of 4-(benzyloxy)-3-methoxybenzoic anhydride

Chemical Property:

• Vapor Pressure: 3.8E-18mmHg at 25°C
• Boiling Point: 676.3°Cat760mmHg
• Flash Point: 286.5°C
• Density: 1.233g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(benzyloxy)-3-methoxybenzoic anhydride

There total 6 articles about 4-(benzyloxy)-3-methoxybenzoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(benzyloxy)-3-methoxybenzoic acid (1486-53-9) → 4-(benzyloxy)-3-methoxybenzoic anhydride (1592-47-8)

Guidance literature:

With pyridine; thionyl chloride; diethyl ether;

DOI:10.1039/jr9300000817

Reference yield:

3-methoxy-4-(phenylmethoxy)benzaldehyde (2426-87-1) → 4-(benzyloxy)-3-methoxybenzoic anhydride (1592-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium permanganate; acetone

2: diethyl ether; thionyl chloride; pyridine

With pyridine; potassium permanganate; thionyl chloride; diethyl ether; acetone;

DOI:10.1039/jr9300000817

Reference yield:

benzyl chloride (100-44-7) → 4-(benzyloxy)-3-methoxybenzoic anhydride (1592-47-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous KOH / 110 - 120 °C

2: potassium permanganate; acetone

3: diethyl ether; thionyl chloride; pyridine

With pyridine; potassium hydroxide; potassium permanganate; thionyl chloride; diethyl ether; acetone;

DOI:10.1039/jr9300000817

upstream raw materials:

4-(benzyloxy)-3-methoxybenzoic acid

3-methoxy-4-benzyloxybenzoyl chloride

3-methoxy-4-(phenylmethoxy)benzaldehyde

benzyl chloride

Downstream raw materials:

2-[4-(benzyloxy)-3-methoxyphenyl]-5,7-dihydroxy-4H-chromen-4-one

4'-(benzyloxy)-7-hydroxy-3,3',5,8-tetramethoxyflavone

2-(4-Benzyloxy-3-methoxy-phenyl)-5,6-dihydroxy-3,7-dimethoxy-chromen-4-one

2-(4-Benzyloxy-3-methoxy-phenyl)-6-hydroxy-3,5,7-trimethoxy-chromen-4-one