Technology Process of Haginin B
There total 4 articles about Haginin B which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 81 percent / H2 / Pd on C (10percent) / diethyl ether
2: 82 percent / K2CO3 / acetone / 1 h
3: NaBH4 / ethanol; tetrahydrofuran / 1 h
4: conc. HCl / acetic acid; ethyl acetate; H2O / 3 h / Heating
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; potassium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; water; acetic acid; ethyl acetate; acetone;
- Guidance literature:
-
With
hydrogenchloride;
In
water; acetic acid; ethyl acetate;
for 3h;
Heating;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 82 percent / K2CO3 / acetone / 1 h
2: NaBH4 / ethanol; tetrahydrofuran / 1 h
3: conc. HCl / acetic acid; ethyl acetate; H2O / 3 h / Heating
With
hydrogenchloride; sodium tetrahydroborate; potassium carbonate;
In
tetrahydrofuran; ethanol; water; acetic acid; ethyl acetate; acetone;