4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-

Base Information

Chemical Name:4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-
CAS No.:83587-62-6
Molecular Formula:C₁₁H₁₄N₄O₄
Molecular Weight:266.257
Hs Code.:
DSSTox Substance ID:DTXSID80232443
ChEMBL ID:CHEMBL1790137

Synonyms:alpha-2'-Deoxy-3-deaza G;83587-62-6;4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-;6-Amino-1,5-dihydro-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)imidazo(4,5-c)pyridin-4-one;SCHEMBL8343204;.alpha.-2'-Deoxy-3-deaza G;CHEMBL1790137;DTXSID80232443;4H-Imidazo[4,5-c]pyridin-4-one, 6-amino-1-(2-deoxy-.alpha.-D-erythro-pentofuranosyl)-1,5-dihydro-;6-Amino-1,5-dihydro-1-(2-deoxy-.alpha.-D-erythro-pentofuranosyl)imidazo[4,5-c]-pyridin-4-one;6-amino-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5H-imidazo[4,5-c]pyridin-4-one

Suppliers and Price of 4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-

Chemical Property:

Vapor Pressure:1.83E-27mmHg at 25°C
Boiling Point:806.4°Cat760mmHg
Flash Point:441.5°C
Density:1.9g/cm³
XLogP3:-1.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:266.10150494
Heavy Atom Count:19
Complexity:416

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(OC1N2C=NC3=C2C=C(NC3=O)N)CO)O
Isomeric SMILES:C1[C@@H]([C@H](O[C@@H]1N2C=NC3=C2C=C(NC3=O)N)CO)O

Technology Process of 4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro-

There total 5 articles about 4H-Imidazo(4,5-c)pyridin-4-one, 6-amino-1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-1,5-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 91741-79-6
5-(cyanomethyl)-1-(2-deoxy-α-D-erythro-pentofuranosyl)imidazole-4-carboxamide

: 83587-62-6
6-amino-1,5-dihydro-1-(2-deoxy-α-D-erythro-pentofuranosyl)imidazo<4,5-c>pyridin-4-one

Guidance literature:: With sodium carbonate; In ethanol; for 0.5h; Heating;
DOI:10.1021/jm00377a002

Reference yield: 75.0%

: 91713-26-7
methyl 5-(cyanomethyl)-1-(2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl)imidazole-4-carboxylate

: 83587-62-6
6-amino-1,5-dihydro-1-(2-deoxy-α-D-erythro-pentofuranosyl)imidazo<4,5-c>pyridin-4-one

: 91741-79-6
5-(cyanomethyl)-1-(2-deoxy-α-D-erythro-pentofuranosyl)imidazole-4-carboxamide

Guidance literature:: With ammonia; at 100 ℃; for 10h;
DOI:10.1021/jm00377a002

Reference yield:

: 3601-89-6,4330-21-6,52304-86-6,3056-12-0,141846-57-3
Hoffer's chlorosugar

: 83587-62-6
6-amino-1,5-dihydro-1-(2-deoxy-α-D-erythro-pentofuranosyl)imidazo<4,5-c>pyridin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) hexamethyldisilazane, ammonium sulfate, 2.) SnCl₄ / 1.) reflux, 4 h, 2.) acetonitrile, dichloroethane, RT, 18 h

2: liquid NH₃ / 6 h / 110 °C

3: 10percent aq. Na₂CO₃ / ethanol / 0.5 h / Heating

With ammonium sulfate; ammonia; tin(IV) chloride; sodium carbonate; 1,1,1,3,3,3-hexamethyl-disilazane; In ethanol;
DOI:10.1021/jm00356a034