Synonyms:2-chloro-1,3-dithiane
The research focuses on the synthesis and reactivity of 2-(1’,3'-dithian-2’-yl)indoles, with the aim of preparing a variety of indole compounds through the reaction of the anion derived from C-2 indole substituted dithiane with appropriately functionalized electrophiles. The study successfully prepared indole dithianes and investigated their reactivity towards different electrophiles, leading to the formation of various compounds. Key chemicals used in the process include N-protected indoles, 2-chloro-1,3-dithiane, phenylsulfonylindole, and n-butyllithium, among others. The conclusions drawn from the research highlight the method's efficiency in preparing 2-(2’-substituted-2’3’-dithian-2’-yl)indoles in three steps from 1-phenylsulfonylindole, showcasing the potential for synthesizing indole alkaloids and related compounds.
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