3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo-

Base Information

Chemical Name:3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo-
CAS No.:576168-07-5
Molecular Formula:C₁₃H₉FN₂OS
Molecular Weight:260.292
Hs Code.:

Synonyms:6-(4-Fluoro-phenyl)-4-methylsulfanyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile;

Suppliers and Price of 3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo-

Chemical Property:

PSA：81.95000
LogP:2.77458

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo-

There total 1 articles about 3-Pyridinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(methylthio)-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 153391-26-5
6-(4-fluorophenyl)-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile

: 6-(4-Fluoro-phenyl)-4-methylsulfanyl-pyridin-2-ylamine

: 576168-07-5
3-cyano-6-(4-fluorophenyl)-4-methylthio-2H-pyridone

Guidance literature:: With urea; at 150 ℃; for 0.133333h;
DOI:10.1055/s-2005-862365

Reference yield: 61.15%

: 576168-07-5
3-cyano-6-(4-fluorophenyl)-4-methylthio-2H-pyridone

: 2-chloro-3-cyano-6-(4-fluorophenyl)-4-methylthiopyridine

Guidance literature:: With trichlorophosphate; at 120 ℃; for 20h;

Reference yield:

: 576168-07-5
3-cyano-6-(4-fluorophenyl)-4-methylthio-2H-pyridone

: 6-(4-fluorophenyl)-4-methylsulfanyl-1H-pyrazolo[3,4-b]pyridin-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 61.15 percent / POCl₃ / 20 h / 120 °C

2: 62.04 percent / hydrazine hydrate / ethanol / 7 h / Heating

With hydrazine hydrate; trichlorophosphate; In ethanol;