4H,9H,10H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,10a-dihydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)-

Base Information

• Chemical Name: 4H,9H,10H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,10a-dihydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)-
• CAS No.: 102916-89-2
• Molecular Formula: C₂₁H₁₈O₅
• Molecular Weight: 350.371
• Mol file: 102916-89-2.mol

Synonyms:4H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,9,10,10a-tetrahydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)-(9CI); 4H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,9,10,10a-tetrahydro-10-hydroxy-9,9-dimethyl-2-phenyl-, [7aS-(7aa,10b,10aa)]-; (-)-Pseudosemiglabrinol; Pseudosemiglabrinol

Chemical Property of 4H,9H,10H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,10a-dihydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4H,9H,10H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,10a-dihydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)-

There total 1 articles about 4H,9H,10H-Furo[3',2':4,5]furo[2,3-h]-1-benzopyran-4-one,7a,10a-dihydro-10-hydroxy-9,9-dimethyl-2-phenyl-, (7aS,10S,10aR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2''',2'''-dimethyl-3'''-acetoxy-tetrahydrofurano-[3'',2''-b]-dihydrofurano-[5'',4''-h]-flavone (51787-32-7) → 2''',2'''-dimethyl-3'''-hydroxy-tetrahydrofurano-[3'',2''-b]-dihydrofurano-[5'',4''-h]-flavone (51787-33-8,102916-89-2)

Guidance literature:

With potassium hydroxide; In ethanol; for 24h;

DOI:10.1016/0031-9422(80)85137-5

Reference yield:

2''',2'''-dimethyl-3'''-hydroxy-tetrahydrofurano-[3'',2''-b]-dihydrofurano-[5'',4''-h]-flavone (51787-33-8,102916-89-2) → tephroglabrin (51787-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 210 mg / acetone / Jones' reagent

2: 146 mg / K₂CO₃ / acetone / 3 h / Heating

With potassium carbonate; In acetone;

DOI:10.1016/0031-9422(80)85137-5

Reference yield:

2''',2'''-dimethyl-3'''-hydroxy-tetrahydrofurano-[3'',2''-b]-dihydrofurano-[5'',4''-h]-flavone (51787-33-8,102916-89-2) → isosemiglabrinone (80159-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: oxidation

2: 10percent alcoholic H₂SO₄ / 1 h / 70 - 75 °C

With sulfuric acid;

DOI:10.1039/P19810002491

upstream raw materials:

2''',2'''-dimethyl-3'''-acetoxy-tetrahydrofurano-[3'',2''-b]-dihydrofurano-[5'',4''-h]-flavone

Downstream raw materials:

tephroglabrin

isosemiglabrinone