Dioscin

Base Information

Chemical Name:Dioscin
CAS No.:19057-60-4
Molecular Formula:C₄₅H₇₂O₁₆
Molecular Weight:869.057
Hs Code.:29389090
European Community (EC) Number:866-819-8
UNII:3B95U4OLWV
Nikkaji Number:J15.520I
Wikidata:Q5807682
Pharos Ligand ID:TZA5JGXD9UBS
Metabolomics Workbench ID:52716
ChEMBL ID:CHEMBL507001
Mol file:19057-60-4.mol

Synonyms:dioscin

Suppliers and Price of Dioscin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dioscin
20mg
$ 320.00

Usbiological
Dioscin
250mg
$ 315.00

Usbiological
Dioscin
25mg
$ 460.00

TRC
Dioscin
2.5g
$ 1255.00

Medical Isotopes, Inc.
Dioscin
50 mg
$ 190.00

Labseeker
DIOSCIN 95
1g
$ 539.00

JR MediChem
Polyphyllin?III 98%
20mg
$ 400.00

DC Chemicals
Dioscin >98%
1 g
$ 800.00

DC Chemicals
Dioscin >98%
250 mg
$ 380.00

CSNpharm
Dioscin
5mg
$ 44.00

Total 121 raw suppliers

Chemical Property of Dioscin

Chemical Property:

Melting Point:294-296 °C
Refractive Index:1.613
PKA:12?+-.0.70(Predicted)
PSA：235.68000
Density:1.39 g/cm³
LogP:1.24170
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated)
XLogP3:1.3
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:7
Exact Mass:868.48203620
Heavy Atom Count:61
Complexity:1600

Purity/Quality:

≥98% ^*data from raw suppliers

Dioscin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1
Isomeric SMILES:C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)C)C)OC1
Description Dioscin is extracted from Dioscorea nipponica. Rhizoma Dioscoreae Nipponicae is the dry rhizome of this plant. It can be orally used to treat joint pain, arthritis, malaria, and chronic bronchitis. In addition, it can also be used externally to treat sore carbuncle swollen. Rhizoma Dioscoreae Nipponicae is commonly used in the northeast region, Shanxi province, and Shandong province of China.
Physical properties Appearance: white powder. Solubility: insoluble in water, petroleum ether, and benzene; soluble in methanol, ethanol, and acetic acid; slightly soluble in acetone and amyl alcohol. Melting point: 294–296℃. Specific optical rotation: ?115° (c?=?0.373, ethanol).
Uses Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins. Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.
Indications This drug was recorded in the national standards for chemical drugs, volume 5. Dioscin tablets, containing total dioscin, are used to treat coronary heart disease, coronary insufficiency, as well as control hyperlipidemia.

Technology Process of Dioscin

There total 41 articles about Dioscin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%