6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid

Base Information

Chemical Name:6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid
CAS No.:58185-82-3
Molecular Formula:C15H22O3
Molecular Weight:250.338
Hs Code.:
DSSTox Substance ID:DTXSID10512644
Wikidata:Q82371983

Synonyms:58185-82-3;6-(2-HYDROXY-3,4,6-TRIMETHYLPHENYL)HEXANOIC ACID;SCHEMBL7319898;DTXSID10512644;YPXATGFVVQQCBY-UHFFFAOYSA-N;6-(2'-hydroxy-3',4',6'-trimethylphenyl)-hexanoic acid;6-(2'-hydroxy-3',4',6'-trimethylphenyl)hexanoic acid;6-(2'-hydroxy-3', 4', 6'-trimethylphenyl)hexanoic acid;6-(2'-hydroxy-3', 4', 6'-trimethylphenyl)- hexanoic acid

Suppliers and Price of 6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:250.15689456
Heavy Atom Count:18
Complexity:265

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1C)O)CCCCCC(=O)O)C

Technology Process of 6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid

There total 5 articles about 6-(2-Hydroxy-3,4,6-trimethylphenyl)hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.4%

: 58185-73-2
5-(2-hydroxy-3,4,6-trimethylbenzoyl)valeric acid

: 58185-82-3
6-(2'-hydroxy-3',4',6'-trimethylphenyl)hexanoic acid

Guidance literature:: With hydrogenchloride; mercury; zinc; In toluene; for 15h; Heating;
DOI:10.1248/cpb.30.2797

Reference yield: 19.0%

: 58185-72-1
ethyl 5-(2-hydroxy-3,4,6-trimethylbenzoyl)pentanoate

: 58185-82-3
6-(2'-hydroxy-3',4',6'-trimethylphenyl)hexanoic acid

: 84978-25-6
6-(2-Hydroxy-3,4,6-trimethyl-phenyl)-hexanoic acid ethyl ester

Guidance literature:: With hydrogenchloride; mercury; zinc; In toluene; for 15h; Heating;
DOI:10.1248/cpb.30.2797

Reference yield:

: 1071-71-2
ethyl 6-chloro-6-oxohexanoate

: 58185-82-3
6-(2'-hydroxy-3',4',6'-trimethylphenyl)hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: AlCl₃ / various solvent(s) / 17 h / 110 - 120 °C / other solvent: nitrobenzene

2: 95.4 percent / Zn-Hg, conc. HCl / toluene / 15 h / Heating

With hydrogenchloride; aluminium trichloride; mercury; zinc; In toluene;
DOI:10.1248/cpb.30.2797