CHEMBRDG-BB 5245988

Base Information

• Chemical Name: CHEMBRDG-BB 5245988
• CAS No.: 58217-60-0
• Molecular Formula: C11H8BrNO2
• Molecular Weight: 266.09100
• Hs Code.: 2932190090
• Mol file: 58217-60-0.mol

Synonyms:5-Brom-furan-2-carbonsaeure-anilid;5-BROMO-N-PHENYL-2-FURAMIDE;N-phenyl-5-bromofuran-2-carboxamide;

Chemical Property of CHEMBRDG-BB 5245988

Chemical Property:

• Vapor Pressure: 0.00621mmHg at 25°C
• Boiling Point: 272.1oC at 760 mmHg
• Flash Point: 118.3oC
• PSA: 42.24000
• Density: 1.59g/cm3
• LogP: 3.36740

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-N-phenylfuran-2-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 5245988

There total 4 articles about CHEMBRDG-BB 5245988 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-bromo-furan-2-carboxylic acid (585-70-6) + aniline (62-53-3) → 5-bromo-furan-2-carboxylic acid anilide (58217-60-0)

Guidance literature:

With dmap; oligomeric alkyl cyclohexylcarbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1021/jo048870c

Reference yield:

5-bromofuran-2-carbonyl chloride (26726-16-9) + aniline (62-53-3) → 5-bromo-furan-2-carboxylic acid anilide (58217-60-0)

Guidance literature:

With 1,4-dioxane;

DOI:10.1021/jo01206a011

Reference yield:

5-bromo-furan-2-carboxylic acid (585-70-6) → 5-bromo-furan-2-carboxylic acid anilide (58217-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 4 h / Heating

2: Et₃N / benzene / 5 h / Ambient temperature

With thionyl chloride; triethylamine; In benzene;

DOI:10.1021/jm970346t

upstream raw materials:

5-bromofuran-2-carbonyl chloride

aniline

5-bromo-furan-2-carboxylic acid

Downstream raw materials:

5-{4-[3-(6-Methylpyridin-2-yl)prop-2-ynylidene]piperidin-1-yl}-N-phenyl-2-furamide

5-Morpholin-4-yl-furan-2-carboxylic acid phenylamide

5-Pyrrolidin-1-yl-furan-2-carboxylic acid phenylamide