4-Methoxyphenyl alpha-phenylbenzeneacetate

Base Information

• Chemical Name: 4-Methoxyphenyl alpha-phenylbenzeneacetate
• CAS No.: 58241-13-7
• Molecular Formula: C₂₁H₁₈O₃
• Molecular Weight: 318.372
• DSSTox Substance ID: DTXSID801283968
• Mol file: 58241-13-7.mol

Synonyms:DTXSID801283968;AKOS002812058;4-Methoxyphenyl alpha-phenylbenzeneacetate;58241-13-7

Chemical Property of 4-Methoxyphenyl alpha-phenylbenzeneacetate

Chemical Property:

• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 318.125594432
• Heavy Atom Count: 24
• Complexity: 357

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 4-Methoxyphenyl alpha-phenylbenzeneacetate

There total 4 articles about 4-Methoxyphenyl alpha-phenylbenzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-diphenylacetic acid (117-34-0) + 4-methoxy-phenol (150-76-5) → 4-methoxyphenyl diphenylacetate (58241-13-7) + N-cyclohexyl-N-[(cyclohexylamino)carbonyl]-diphenylacetamide (31280-18-9)

Guidance literature:

In acetonitrile; at 25 ℃; for 1h;

DOI:10.1039/b312559a

Reference yield:

2,2-diphenylacetic acid (117-34-0) → 4-methoxyphenyl diphenylacetate (58241-13-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.14 g / DCC

2: DCC

With dicyclohexyl-carbodiimide;

DOI:10.1039/b312559a

Reference yield:

diphenylacetic anhydride (1760-46-9) + 4-methoxy-phenol (150-76-5) → 4-methoxyphenyl diphenylacetate (58241-13-7)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1039/b312559a

upstream raw materials:

diphenylacetic anhydride

4-methoxy-phenol

2,2-diphenylacetic acid