Synonyms:Thieno[2,3-c]pyridazine;58247-21-5;SCHEMBL2330504;DTXSID80598935;AKOS006308195;DB-299293
99% *data from raw suppliers
There total 1 articles about Thieno[2,3-c]pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
Reference yield: 58.0%
The study investigates the synthesis, reactions, and antimicrobial activity of thieno[2,3-c]pyridazine derivatives. The research involves the reaction of N1-(un)substituted 4-aminosulfonamide with 6-chloropyridothienopyridazine (5) and 8-chloropyrimidothienopyridazine (14) to produce 6-substituted aminopyridothienopyridazine (9) and 8-substituted aminopyrimidothienopyridazine (16) respectively. These derivatives are characterized by analytical and spectroscopic studies and tested for their in vitro antibacterial and antifungal activity against various microorganisms. The study also explores the synthesis of other related compounds such as 7-cyano-3,4,8-triphenylpyrido[2',3' : 4,5]thieno[2,3-c]pyridazin-6(5H)-one (4), 6-chloro-7-cyano-3,4,8-triphenylpyrido[2',3' : 4,5]thieno[2,3-c]pyridazine (5), and their various substituted derivatives. The antimicrobial activity of the synthesized compounds is evaluated against Gram positive bacteria (Staphylococcus aureus, Bacillus subtilis), Gram negative bacteria (Escherichia coli, Pseudomonas aeruginosa), yeast (Candida albicans), and fungi (Aspergillus niger). The results indicate that several compounds exhibit high and very high antimicrobial activity against the tested microorganisms, comparable to standard antibacterial and antifungal agents.
What can I do for you?
Get Best Price
Total 8 Pictures about this product
