1-Hydroxyindeno(1,2,3-cd)pyrene

Base Information

• Chemical Name: 1-Hydroxyindeno(1,2,3-cd)pyrene
• CAS No.: 99520-65-7
• Molecular Formula: C₂₂H₁₂O
• Molecular Weight: 292.337
• DSSTox Substance ID: DTXSID30912647
• Wikidata: Q82882980
• Mol file: 99520-65-7.mol

Synonyms:1-Hydroxyindeno(1,2,3-cd)pyrene;99520-65-7;1-HYDROXYINDENO[1,2,3-CD]PYRENE;CCRIS 2551;DTXSID30912647;Indeno[1,2,3-cd]pyren-11-ol

Chemical Property of 1-Hydroxyindeno(1,2,3-cd)pyrene

Chemical Property:

• Vapor Pressure: 6.22E-13mmHg at 25°C
• Boiling Point: 555.2°Cat760mmHg
• Flash Point: 264.8°C
• Density: 1.47g/cm³
• XLogP3: 6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 292.088815002
• Heavy Atom Count: 23
• Complexity: 486

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC4=CC=CC5=C4C6=C3C2=C(C=C6C=C5)O

Technology Process of 1-Hydroxyindeno(1,2,3-cd)pyrene

There total 3 articles about 1-Hydroxyindeno(1,2,3-cd)pyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-1,2-diacetoxy-1,2-dihydroindeno<1,2,3-cd>pyrene (102420-53-1) → 1-hydroxyindeno<1,2,3-cd>pyrene (99520-65-7)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; In tetrahydrofuran; methanol; at 60 - 100 ℃; Yield given;

DOI:10.1021/jo00363a005

Reference yield:

Indeno[1,2,3-cd]pyrene (193-39-5) → 1-hydroxyindeno<1,2,3-cd>pyrene (99520-65-7)

Guidance literature:

Multi-step reaction with 3 steps

1: osmium tetraoxide / pyridine; benzene / 504 h / Ambient temperature

2: pyridine / 18 h / Ambient temperature

3: tetrabutylammonium hydroxide / tetrahydrofuran; methanol / 60 - 100 °C

With pyridine; osmium(VIII) oxide; tetra(n-butyl)ammonium hydroxide; In tetrahydrofuran; pyridine; methanol; benzene;

DOI:10.1021/jo00363a005

Reference yield:

cis-1,2-dihydro-1,2-dihydroxyindeno<1,2,3-cd>pyrene (102420-54-2,99520-57-7) → 1-hydroxyindeno<1,2,3-cd>pyrene (99520-65-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 18 h / Ambient temperature

2: tetrabutylammonium hydroxide / tetrahydrofuran; methanol / 60 - 100 °C

With pyridine; tetra(n-butyl)ammonium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1021/jo00363a005

upstream raw materials:

cis-1,2-diacetoxy-1,2-dihydroindeno<1,2,3-cd>pyrene

Indeno[1,2,3-cd]pyrene

cis-1,2-dihydro-1,2-dihydroxyindeno<1,2,3-cd>pyrene