1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride

Base Information

Chemical Name:1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride
CAS No.:165377-44-6
Molecular Formula:C₂₃H₃₂N₂O₂*2ClH
Molecular Weight:441.441
Hs Code.:2933599090
UNII:B66RO93FXQ
DSSTox Substance ID:DTXSID60433294
Wikidata:Q72468307
ChEMBL ID:CHEMBL3216524
Mol file:165377-44-6.mol

Synonyms:(11C)SA4503;1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride;cutamesine;SA 4503;SA-4503;SA4503

Suppliers and Price of 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SA 4503 dihydrochloride
10mg
$ 432.00

TRC
SA4503DiHydrochloride
10mg
$ 100.00

Tocris
SA4503dihydrochloride ≥98%(HPLC)
10
$ 193.00

Sigma-Aldrich
SA4503 ≥98% (HPLC)
25mg
$ 355.00

Sigma-Aldrich
SA4503 ≥98% (HPLC)
5mg
$ 87.50

DC Chemicals
SA45032HCl >98%
100 mg
$ 500.00

DC Chemicals
SA45032HCl >98%
1 g
$ 1600.00

CSNpharm
SA45032HCl
5mg
$ 76.00

Crysdot
SA4503dihydrochloride 98+%
50mg
$ 516.00

ChemScene
Cutamesinedihydrochloride 99.48%
10mg
$ 143.00

Total 28 raw suppliers

Chemical Property of 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride

Chemical Property:

Vapor Pressure:4.25E-10mmHg at 25°C
Melting Point:250-252°C
Boiling Point:499.2°C at 760 mmHg
Flash Point:137.3°C
PSA：24.94000
LogP:4.97650
Storage Temp.:2-8°C
Solubility.:Soluble in DMSO (up to 5 mg/ml) or in Water (up to at least 25 mg/ml)..
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:440.1997337
Heavy Atom Count:29
Complexity:392

Purity/Quality:

99%, ^*data from raw suppliers

SA 4503 dihydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCN2CCN(CC2)CCCC3=CC=CC=C3)OC.Cl.Cl
Recent EU Clinical Trials:A Randomized, Double-Blind, Placebo-Controlled, Ascending Dose, Phase IIa Study of Safety and Motor Function Restoration in Subjects Treated with SA4503 following Acute Ischemic Stroke
Description SA4503 (165377-44-6) is a potent and selective sigma 1 agonist (σ1 IC50?= 17.4 nM, σ2 IC50?= 1784 nM).1?It has been investigated as a cognition enhancer2,3, antidepressant4,5, anti-addiction agent6, and neuroprotectant7-10.
Uses SA 4503 Dihydrochloride is a novel and selective σ1 receptor agonist.

Technology Process of 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride

There total 1 articles about 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: