cis-3,4',5-Trimethoxy-3'-hydroxystilbene

Base Information

• Chemical Name: cis-3,4',5-Trimethoxy-3'-hydroxystilbene
• CAS No.: 586410-08-4
• Molecular Formula: C17H18O4
• Molecular Weight: 286.328
• DSSTox Substance ID: DTXSID80435775
• Nikkaji Number: J435.583K
• Wikidata: Q82250875
• ChEMBL ID: CHEMBL116888
• Mol file: 586410-08-4.mol

Synonyms:cis-3,4',5-trimethoxy-3'-hydroxystilbene;stilbene 6c

Chemical Property of cis-3,4',5-Trimethoxy-3'-hydroxystilbene

Chemical Property:

• Melting Point: N /A
• Boiling Point: 472.8±45.0 °C(Predicted)
• PKA: 9.68±0.10(Predicted)
• PSA: 47.92000
• Density: 1.177±0.06 g/cm3(Predicted)
• LogP: 3.58840
• Storage Temp.: Amber Vial, -20°C Freezer
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 286.12050905
• Heavy Atom Count: 21
• Complexity: 319

Purity/Quality:

97% ^*data from raw suppliers

cis-3,4'',5-Trimethoxy-3''-hydroxystilbene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=CC2=CC(=CC(=C2)OC)OC)O
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C\C2=CC(=CC(=C2)OC)OC)O
• Uses: A derivative of Resveratrol which shows apoptotic activity at nanomolar concentrations. Has an IC50= 0.3. It showed activity toward resistant HL60R cells and their activity was higher than that of several classic chemotherapeutic agents A derivative of Resveratrol which shows apoptotic activity at nanomolar concentrations. Has an IC50= 0.3. It showed activity toward resistant HL60R cells and their activity was higher than that of several classic chemotherapeutic agents.

Technology Process of cis-3,4',5-Trimethoxy-3'-hydroxystilbene

There total 7 articles about cis-3,4',5-Trimethoxy-3'-hydroxystilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

cis-3,4',5-trimethoxy-3'-tert-butyldimethylsilyloxystilbene (586410-23-3) → (Z)-3′-hydroxyl-3,4′,5-trimethoxystilbene (586410-08-4)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2006.08.088

Reference yield: 85.0%

(E)-2-(3'-hydroxy-4'-methoxyphenyl)-3-(3',5'-dimethoxyphenyl)acrylic acid (1340494-43-0) → (Z)-3′-hydroxyl-3,4′,5-trimethoxystilbene (586410-08-4)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; at 180 - 190 ℃; Microwave irradiation; Inert atmosphere; Green chemistry;

DOI:10.1039/c3ob41588k

Reference yield: 84.0%

α-(3,5-Dimethoxyphenyl)-3-hydroxy-4-methoxyzimtsaeure (39500-08-8) → (Z)-3′-hydroxyl-3,4′,5-trimethoxystilbene (586410-08-4)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; at 180 - 190 ℃; Reagent/catalyst; Microwave irradiation; Inert atmosphere; Green chemistry;

DOI:10.1039/c3ob41588k

upstream raw materials:

cis-3,4',5-trimethoxy-3'-tert-butyldimethylsilyloxystilbene

isovanillin

3,5-dimethoxybenzyl bromide

p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 586410-08-4 CIS-3,4',5-TRIMETHOXY-3'-HYDROXYSTILBENE

Send

Send

Metric Ton KG G Pound L ML

Send

Send