CIS-3,4',5-TRIMETHOXY-3'-AMINOSTILBENE

Base Information

• Chemical Name: CIS-3,4',5-TRIMETHOXY-3'-AMINOSTILBENE
• CAS No.: 586410-12-0
• Molecular Formula: C17H19NO3
• Molecular Weight: 285.33800
• Mol file: 586410-12-0.mol

Synonyms:cis-3,4',5-Trimethoxy-3'-aminostilbene;

Chemical Property of CIS-3,4',5-TRIMETHOXY-3'-AMINOSTILBENE

Chemical Property:

• PSA: 53.71000
• LogP: 4.04620

Purity/Quality:

97% ^*data from raw suppliers

cis-3,4'',5-Trimethoxy-3''-aminostilbene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS-3,4',5-TRIMETHOXY-3'-AMINOSTILBENE

There total 3 articles about CIS-3,4',5-TRIMETHOXY-3'-AMINOSTILBENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

(Z)-1-[2-(3,5-dimethoxyphenyl)-ethenyl]-4-methoxy-3-nitrobenzene → (Z)-5-(3,5-dimethoxystyryl)-2-methoxyaniline (586410-12-0)

Guidance literature:

With sodium dithionite; In acetone; Heating;

DOI:10.1021/jm030785u

Reference yield:

(3,5-dimethoxybenzyl)triphenylphosphonium bromide (24131-30-4) → (Z)-5-(3,5-dimethoxystyryl)-2-methoxyaniline (586410-12-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C

1.2: 27 percent / tetrahydrofuran; hexane / 20 °C

2.1: 32 percent / aq. Na₂S₂O₄ / acetone / Heating

With n-butyllithium; sodium dithionite; In tetrahydrofuran; hexane; acetone;

DOI:10.1021/jm030785u

Reference yield:

4-methoxy-3-nitrobenzaldehyde (31680-08-7) → (Z)-5-(3,5-dimethoxystyryl)-2-methoxyaniline (586410-12-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C

1.2: 27 percent / tetrahydrofuran; hexane / 20 °C

2.1: 32 percent / aq. Na₂S₂O₄ / acetone / Heating

With n-butyllithium; sodium dithionite; In tetrahydrofuran; hexane; acetone;

DOI:10.1021/jm030785u

upstream raw materials:

(3,5-dimethoxybenzyl)triphenylphosphonium bromide

4-methoxy-3-nitrobenzaldehyde

Downstream raw materials:

(Z)-{5-[2-(3,5-dimethoxy-phenyl)-vinyl]-2-methoxy-phenyl}-carbamic acid 2-morpholin-4-yl-ethyl ester oxalate

(Z) 1-{5-[2-(3,5-dimethoxy-phenyl)-vinyl]-2-methoxy-phenyl}-3-(2-morpholin-4-yl-ethyl)-urea hydrochloride

(Z)-{5-[2-(3,5-dimethoxyphenyl)-ethenyl]-2-methoxyphenyl}carbamic acid 2-[2-(2-hydroxyethoxy)ethoxy]ethyl ester

(Z)-1-{5-[2-(3,5-dimethoxyphenyl)-ethenyl]-2-methoxyphenyl}-3-(2-morpholin-4-yl-ethyl)-urea

Refernces