4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline

Base Information

Chemical Name:4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline
CAS No.:586410-15-3
Molecular Formula:C16H17NO2
Molecular Weight:255.316
Hs Code.:
DSSTox Substance ID:DTXSID80708537

Synonyms:MFCD16038082;DTXSID80708537;SY271644;4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline;4-[2-(3,5-dimethoxy-phenyl)vinyl]phenylamine

Suppliers and Price of 4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:255.125928785
Heavy Atom Count:19
Complexity:273

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1)C=CC2=CC=C(C=C2)N)OC

Technology Process of 4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline

There total 12 articles about 4-[2-(3,5-Dimethoxyphenyl)ethenyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 586410-18-6
(E)-1,3-dimethoxy-5-(4-nitrostyryl)benzene

: 586410-15-3
1-[(E)-2-(4-aminophenyl)ethenyl]-3,5-dimethoxybenzene

Guidance literature:: With tin(II) chloride dihdyrate; In ethyl acetate; for 5h; Reflux; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.10.028

Reference yield:

: 586410-18-6
(E)-1,3-dimethoxy-5-(4-nitrostyryl)benzene

: (Z)-4-(3,5-dimethoxystyryl)aniline

: 586410-15-3
1-[(E)-2-(4-aminophenyl)ethenyl]-3,5-dimethoxybenzene

Guidance literature:: With sodium dithionite; In water; acetone; at 50 ℃; for 1h; Heating / reflux;

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 586410-15-3
1-[(E)-2-(4-aminophenyl)ethenyl]-3,5-dimethoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C

1.2: 46 percent / tetrahydrofuran; hexane / 20 °C

2.1: 37 percent / aq. Na₂S₂O₄ / acetone / Heating

With n-butyllithium; sodium dithionite; In tetrahydrofuran; hexane; acetone;
DOI:10.1021/jm030785u