2-amino-N-(quinolin-8-yl)acetamide

Base Information

Chemical Name:2-amino-N-(quinolin-8-yl)acetamide
CAS No.:587832-36-8
Molecular Formula:C11H11N3O
Molecular Weight:201.228
Hs Code.:
European Community (EC) Number:863-362-6
Nikkaji Number:J1.952.440J

Synonyms:2-amino-N-(quinolin-8-yl)acetamide;587832-36-8;2-amino-N-quinolin-8-ylacetamide;glycine-N-8-quinolylamide;AKOS000194661;CS-0253174;EN300-62644;Z317067342

Suppliers and Price of 2-amino-N-(quinolin-8-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-amino-N-(quinolin-8-yl)acetamide
50mg
$ 75.00

AK Scientific
2-Amino-N-(quinolin-8-yl)acetamide
1g
$ 289.00

AK Scientific
2-Amino-N-(quinolin-8-yl)acetamide
500mg
$ 226.00

AK Scientific
2-Amino-N-(quinolin-8-yl)acetamide
100mg
$ 148.00

Total 2 raw suppliers

Chemical Property of 2-amino-N-(quinolin-8-yl)acetamide

Chemical Property:

Melting Point:108 - 110 °C
PSA：68.01000
LogP:1.90530
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:201.090211983
Heavy Atom Count:15
Complexity:232

Purity/Quality:

99% ^*data from raw suppliers

2-amino-N-(quinolin-8-yl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)NC(=O)CN)N=CC=C2

Technology Process of 2-amino-N-(quinolin-8-yl)acetamide

There total 4 articles about 2-amino-N-(quinolin-8-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 539857-70-0
tert-butyl (2-oxo-2-(quinolin-8-ylamino)ethyl)carbamate

: 587832-36-8
2-amino-N-(quinolin-8-yl)acetamide

Guidance literature:: With trifluoroacetic acid; In chloroform; for 24h;
DOI:10.1021/jm020593j

Reference yield: 72.0%

: 1093981-78-2
2-azido-N-(quinolin-8-yl)acetamide

: 587832-36-8
2-amino-N-(quinolin-8-yl)acetamide

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water; at 20 - 85 ℃;
DOI:10.1039/c004871b

Reference yield:

: 578-66-5
8-amino quinoline

: 587832-36-8
2-amino-N-(quinolin-8-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloroformic acid ethyl ester; triethylamine / tetrahydrofuran / 1 h / -15 °C / Inert atmosphere

1.2: 16 h / -15 - 24 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 16 h / 0 - 24 °C

With chloroformic acid ethyl ester; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jacs.7b08383