4-Aminopyridine-2,6-diol

Base Information

• Chemical Name: 4-Aminopyridine-2,6-diol
• CAS No.: 17325-31-4
• Molecular Formula: C₅H₆N₂O₂
• Molecular Weight: 126.115
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID501298110
• Mol file: 17325-31-4.mol

Synonyms:4-Aminopyridine-2,6-diol;17325-31-4;4-amino-6-hydroxy-1H-pyridin-2-one;2(1H)-Pyridinone,4-amino-6-hydroxy-(9CI);2.6-Dioxy-4-aminopyridin;SCHEMBL7690577;DTXSID501298110;4-Amino-6-hydroxy-2(1H)-pyridone;4-amino-6-hydroxy-2(1H)-Pyridinone;AKOS006338511;EN300-37080455

Chemical Property of 4-Aminopyridine-2,6-diol

Chemical Property:

• PSA: 79.37000
• LogP: 0.65620
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 126.042927438
• Heavy Atom Count: 9
• Complexity: 205

Purity/Quality:

99% ^*data from raw suppliers

4-amino-1,2,3,6-tetrahydropyridine-2,6-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(NC1=O)O)N

Technology Process of 4-Aminopyridine-2,6-diol

There total 6 articles about 4-Aminopyridine-2,6-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperidine-2,4,6-trione (5768-12-7) → 2,6-Dihydroxy-4-amino-pyridin (17325-31-4)

Guidance literature:

With ammonium acetate; at 120 - 140 ℃;

Reference yield:

→ 2,6-Dihydroxy-4-amino-pyridin (17325-31-4)

Guidance literature:

With sodium carbonate;

Reference yield:

→ 2,6-Dihydroxy-4-amino-pyridin (17325-31-4)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

pyridine-2,4,6-triol

ammonium acetate

piperidine-2,4,6-trione

Downstream raw materials:

2,3,6-trichloro-[4]pyridylamine

2,3,5,6-tetrachloro-pyridin-4-ylamine

piperidine-2,4,6-trione