(S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Base Information

Chemical Name:(S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane
CAS No.:591235-75-5
Molecular Formula:C12H15FO3
Molecular Weight:226.248
Hs Code.:
DSSTox Substance ID:DTXSID401187590

Synonyms:SCHEMBL9774729;LAHQLGXFWFVYBF-NSHDSACASA-N;(S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane;DTXSID401187590;591235-75-5;(4S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Suppliers and Price of (S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:226.10052250
Heavy Atom Count:16
Complexity:224

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(OCC(O1)COC2=CC=C(C=C2)F)C
Isomeric SMILES:CC1(OC[C@@H](O1)COC2=CC=C(C=C2)F)C

Technology Process of (S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

There total 2 articles about (S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 371-41-5
4-Fluorophenol

: 23788-74-1,7305-59-1
(R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate

: 591235-75-5
(S)-4-[(4-fluorophenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

Guidance literature:: 4-Fluorophenol; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

(R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/S0957-4166(03)00157-5