1-Amino-6-bromonaphthalene

Base Information

• Chemical Name: 1-Amino-6-bromonaphthalene
• CAS No.: 591253-73-5
• Molecular Formula: C10H8BrN
• Molecular Weight: 222.084
• Mol file: 591253-73-5.mol

Synonyms:5-amino-2-bromo-naphthalene;1-Amino-6-bromonaphthalene;

Chemical Property of 1-Amino-6-bromonaphthalene

Chemical Property:

• Boiling Point: 358.0±17.0 °C(Predicted)
• PKA: 3.41±0.10(Predicted)
• PSA: 26.02000
• Density: 1.563±0.06 g/cm3(Predicted)
• LogP: 3.76570

Purity/Quality:

98% ^*data from raw suppliers

1-Amino-6-bromonaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Amino-6-bromonaphthalene

There total 1 articles about 1-Amino-6-bromonaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-bromo-1-aminonaphthalene (591253-73-5)

Guidance literature:

Reference yield: 89.0%

6-bromo-1-aminonaphthalene (591253-73-5) + 1-Bromo-2-iodobenzene (583-55-1) → C16H11Br2N

Guidance literature:

With palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; at 110 ℃; for 6h;

Reference yield:

6-bromo-1-aminonaphthalene (591253-73-5) → 6-bromo-naphthalene-1,2-diamine (1241377-74-1)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; dmap / dichloromethane / 3 h / 20 °C / Industrial scale

2: nitric acid / acetic anhydride; acetic acid / 11 h / 35 - 45 °C / Industrial scale

3: ammonium chloride; water; iron / tetrahydrofuran / 6 h / 55 - 65 °C / Industrial scale

4: hydrogenchloride / methanol / 5 h / 55 - 65 °C / Industrial scale

With hydrogenchloride; dmap; water; nitric acid; iron; ammonium chloride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; acetic anhydride; acetic acid;

Downstream raw materials:

6-bromo-naphthalene-1,2-diamine

Refernces