Propanedioic acid, (carboxymethoxy)methyl-

Base Information

• Chemical Name: Propanedioic acid, (carboxymethoxy)methyl-
• CAS No.: 59216-71-6
• Molecular Formula: C₆H₈O₇
• Molecular Weight: 192.125
• Mol file: 59216-71-6.mol

Synonyms:

Chemical Property of Propanedioic acid, (carboxymethoxy)methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanedioic acid, (carboxymethoxy)methyl-

There total 1 articles about Propanedioic acid, (carboxymethoxy)methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

triethyl 2-oxa-1,3,3-butanetricarboxylate (41358-69-4) → 2-carboxymethoxy-2-methylmalonic acid (59216-71-6)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃;

DOI:10.1002/poc.591

Reference yield:

2-carboxymethoxy-2-methylmalonic acid (59216-71-6) → 2-(methoxycarbonylmethoxy)-2-methylmalonic acid

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / trifluoroacetic anhydride / CH₂Cl₂ / 0.5 h / 20 °C

2: 99 percent / 3 h / 20 °C

With trifluoroacetic anhydride; In dichloromethane;

DOI:10.1002/poc.591

upstream raw materials:

triethyl 2-oxa-1,3,3-butanetricarboxylate

Refernces