N,N-Dimethyl-N'-(4-nitrophenyl)formamidine

Base Information

• Chemical Name: N,N-Dimethyl-N'-(4-nitrophenyl)formamidine
• CAS No.: 1205-59-0
• Molecular Formula: C9H11 N3 O2
• Molecular Weight: 193.205
• Hs Code.: 2925290090
• Mol file: 1205-59-0.mol

Synonyms:Formamidine,N,N-dimethyl-N'-(p-nitrophenyl)- (7CI,8CI);N,N-Dimethyl-N'-(p-nitrophenyl)formamidine; NSC 150694;N'-(p-Nitrophenyl)-N,N-dimethylformamidine

Chemical Property of N,N-Dimethyl-N'-(4-nitrophenyl)formamidine

Chemical Property:

• Boiling Point: 319.3oC at 760 mmHg
• Flash Point: 146.9oC
• PSA: 61.42000
• Density: 1.14g/cm3
• LogP: 2.33940

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-Dimethyl-N'-(4-nitrophenyl)formamidine

There total 8 articles about N,N-Dimethyl-N'-(4-nitrophenyl)formamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-dimethyl-formamide dimethyl acetal (4637-24-5) + 4-nitro-aniline (100-01-6,104810-17-5) → N1,N1-dimethyl-N2-(4-nitro-phenyl)-formamidine (1205-59-0)

Guidance literature:

In neat (no solvent); at 80 ℃; Microwave irradiation;

DOI:10.1016/j.tet.2020.131205

Reference yield: 72.0%

N-(4-Nitrophenyl)acetamide (104-04-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N1,N1-dimethyl-N2-(4-nitro-phenyl)-formamidine (1205-59-0)

Guidance literature:

With trichlorophosphate; at 100 ℃; for 1.25h; further temperature;

DOI:10.1039/P19810001520

Reference yield: 45.0%

N-(4-Nitrophenyl)acetamide (104-04-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → N1,N1-dimethyl-N2-(4-nitro-phenyl)-formamidine (1205-59-0) + (E)-3-Dimethylamino-2-formyl-N-(4-nitro-phenyl)-acrylamide (78708-10-8) + 4-nitro-aniline (100-01-6,104810-17-5) + 3-dimethylaminoacrolein (927-63-9)

Guidance literature:

With trichlorophosphate; at 75 ℃; for 1.5h;

DOI:10.1039/P19810001520

upstream raw materials:

4-nitro-aniline

N,N-dimethyl-formamide

N,N-dimethylformamide diethyl diacetal

N,N-dimethyl-formamide dimethyl acetal

Downstream raw materials:

2-cyano-3-(4-nitro-phenylamino)-acrylic acid ethyl ester

N-(4-nitrophenyl)methanethioamide