1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione

Base Information

• Chemical Name: 1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione
• CAS No.: 59426-87-8
• Molecular Formula: C26H18O4
• Molecular Weight: 394.427
• DSSTox Substance ID: DTXSID20512771
• Wikidata: Q82372159
• Mol file: 59426-87-8.mol

Synonyms:59426-87-8;1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione;DTXSID20512771

Chemical Property of 1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione

Chemical Property:

• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 394.12050905
• Heavy Atom Count: 30
• Complexity: 775

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=C3C4=CC=CC=C4C(=O)C3=C(C2=O)C5=CC=C(C=C5)OC

Technology Process of 1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione

There total 1 articles about 1,3-Bis(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

indan-1,2,3-trione hydrate (485-47-2) + 1,3-bis(4-methoxyphenyl)acetone (29903-09-1) → 1,3-bis-(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione (59426-87-8)

Guidance literature:

indan-1,2,3-trione hydrate; 1,3-bis(4-methoxyphenyl)acetone; In ethanol; at 20 ℃; for 0.5h; Inert atmosphere;

With tetra(n-butyl)ammonium hydroxide; In ethanol; water; for 1h; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.7b03686

Reference yield: 95.0%

1,3-bis-(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione (59426-87-8) + bicyclo[2.2.1]hepta-2,5-diene (121-46-0) → 1,4-bis(4-methoxyphenyl)-9H-fluoren-9-one (78237-29-3)

Guidance literature:

for 3h; Heating;

Reference yield: 82.0%

tetrathiafulvalene (31366-25-3) + 1,3-bis-(4-methoxyphenyl)cyclopenta[a]indene-2,8-dione (59426-87-8) → 1,4-bis(4-methoxyphenyl)-9H-fluoren-9-one (78237-29-3)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; for 16h; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.7b03686

upstream raw materials:

indan-1,2,3-trione hydrate

1,3-bis(4-methoxyphenyl)acetone

Downstream raw materials:

1,4-Bis-(4-methoxy-phenyl)-2,3-di-p-tolyl-fluoren-9-one

5,10-bis(4-methoxyphenyl)-11H-benzo[b]-fluoren-11-one

1,4-bis(4-methoxyphenyl)-9H-fluoren-9-one

1,4-Bis-(4-methoxy-phenyl)-2,3-diphenyl-fluoren-9-one