Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)

Base Information

Chemical Name:Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)
CAS No.:594860-94-3
Molecular Formula:C₂H₄O₂*C₂₈H₄₁N₃O₇
Molecular Weight:591.702
Hs Code.:

Glycine,
N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]
amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)

Synonyms:

Suppliers and Price of Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt)

There total 10 articles about Glycine, N-[[[3-[4-[[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl] amino]hexyl]oxy]butyl]phenyl]amino]carbonyl]-, monoacetate (salt) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 457635-26-6
3-(3-iodophenyl)imidazolidine-2,4-dione

: 594860-94-3
N-({[3-(4-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)hexyl]oxy}butyl)phenyl]amino}carbonyl)glycine acetic acid salt

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 24 h / Inert atmosphere

1.2: 22 h / 20 °C

2.1: platinum(IV) oxide; hydrogen / ethyl acetate / 3 h

3.1: water

4.1: water / 75 °C

With platinum(IV) oxide; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; hydrogen; N-ethyl-N,N-diisopropylamine; In water; ethyl acetate; N,N-dimethyl-formamide; 1.1: Sonogashira coupling;
DOI:10.1016/j.bmc.2011.05.064

Reference yield:

: 457635-17-5
ethyl N-{[(3-iodophenyl)amino]carbonyl}glycinate

: 594860-94-3
N-({[3-(4-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)hexyl]oxy}butyl)phenyl]amino}carbonyl)glycine acetic acid salt

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C

2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 24 h / Inert atmosphere

2.2: 22 h / 20 °C

3.1: platinum(IV) oxide; hydrogen / ethyl acetate / 3 h

4.1: water

5.1: water / 75 °C

With platinum(IV) oxide; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; hydrogen; sodium hydride; N-ethyl-N,N-diisopropylamine; In water; ethyl acetate; N,N-dimethyl-formamide; mineral oil; 2.1: Sonogashira coupling;
DOI:10.1016/j.bmc.2011.05.064

Reference yield:

: 457631-24-2
3-(3-{4-[(6-{[(2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]amino}hexyl)oxy]butyl}phenyl)imidazolidine-2,4-dione

: 594860-94-3
N-({[3-(4-{[6-({(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)hexyl]oxy}butyl)phenyl]amino}carbonyl)glycine acetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: water

2: water / 75 °C

With water; In water;
DOI:10.1016/j.bmc.2011.05.064