1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide

Base Information

Chemical Name:1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide
CAS No.:59547-43-2
Molecular Formula:C15H18N2O
Molecular Weight:242.321
Hs Code.:
DSSTox Substance ID:DTXSID90578940

Synonyms:59547-43-2;1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide;DTXSID90578940

Suppliers and Price of 1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:242.141913202
Heavy Atom Count:18
Complexity:352

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=CN(C=CC1)CC2=CC=CC=C2

Technology Process of 1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide

There total 5 articles about 1-Benzyl-N,N-dimethyl-1,4-dihydropyridine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-benzyl-3-dimethylcarbamoylpyridinium bromide

: 59547-43-2
1-benzyl-1,4-dihydro-pyridine-3-carboxylic acid dimethylamide

: 1-Benzyl-1,6-dihydro-pyridine-3-carboxylic acid dimethylamide

Guidance literature:: With EtCH(OMgBr)2; In tetrahydrofuran; at 90 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1002/(SICI)1521-3773(19980605)37:10<1410::AID-ANIE1410>3.0.CO;2-G

Reference yield:

: 1-benzyl-3-dimethylcarbamoylpyridinium bromide

: 59547-43-2
1-benzyl-1,4-dihydro-pyridine-3-carboxylic acid dimethylamide

Guidance literature:: With sodium dithionite; water; sodium carbonate;
DOI:10.1021/jo00133a014

Reference yield:

: 6972-69-6
N,N-dimethylnicotinamide

: 100-44-7
benzyl chloride

: C₁₅H₁₁N₃*C₁₀H₈N₂*Ru⁽²⁺⁾*C₁₅H₁₈N₂O

: 59547-43-2
1-benzyl-1,4-dihydro-pyridine-3-carboxylic acid dimethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 12 h / Reflux

2: N,N-dimethyl-formamide / 26.84 °C / Inert atmosphere

In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.organomet.5b00713