2-Buten-1-one, 1,4,4,4-tetraphenyl-, (2E)-

Base Information

• Chemical Name: 2-Buten-1-one, 1,4,4,4-tetraphenyl-, (2E)-
• CAS No.: 595565-36-9
• Molecular Formula: C₂₈H₂₂O
• Molecular Weight: 374.482
• Mol file: 595565-36-9.mol

Synonyms:

Chemical Property of 2-Buten-1-one, 1,4,4,4-tetraphenyl-, (2E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Buten-1-one, 1,4,4,4-tetraphenyl-, (2E)-

There total 4 articles about 2-Buten-1-one, 1,4,4,4-tetraphenyl-, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1,1,4-tetraphenylbutan-1-one (96277-60-0) → trans-1,1,1,4-tetraphenylbut-2-en-1-one (595565-36-9)

Guidance literature:

With selenium(IV) oxide; acetic acid; In tert-butyl alcohol; for 48h; Heating;

DOI:10.1139/v03-030

Reference yield:

1-Bromo-3-phenylpropane (637-59-2) → trans-1,1,1,4-tetraphenylbut-2-en-1-one (595565-36-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Na/Hg / diethyl ether / 3 h

1.2: 53 percent / diethyl ether / 4 h / 20 °C

2.1: 75 percent / chromium trioxide; aq. t-BuOOH / CH₂Cl₂ / 36 h / 20 °C

3.1: selenium dioxide; glacial acetic acid / 2-methyl-propan-2-ol / 48 h / Heating

With chromium(VI) oxide; tert.-butylhydroperoxide; sodium amalgam; selenium(IV) oxide; acetic acid; In diethyl ether; dichloromethane; tert-butyl alcohol;

DOI:10.1139/v03-030

Reference yield:

1,1,1,4-tetraphenylbutane (88689-62-7) → trans-1,1,1,4-tetraphenylbut-2-en-1-one (595565-36-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / chromium trioxide; aq. t-BuOOH / CH₂Cl₂ / 36 h / 20 °C

2: selenium dioxide; glacial acetic acid / 2-methyl-propan-2-ol / 48 h / Heating

With chromium(VI) oxide; tert.-butylhydroperoxide; selenium(IV) oxide; acetic acid; In dichloromethane; tert-butyl alcohol;

DOI:10.1139/v03-030

upstream raw materials:

1,1,1,4-tetraphenylbutan-1-one

1-Bromo-3-phenylpropane

1,1,1,4-tetraphenylbutane

trityl chloride

Downstream raw materials:

trans-3-Benzoyl-1,2,2-triphenylcyclopropane