4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol

Base Information

Chemical Name:4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol
CAS No.:59565-53-6
Molecular Formula:C8H7N3OS
Molecular Weight:193.229
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40419970
Wikidata:Q82231204
ChEMBL ID:CHEMBL4471826
Mol file:59565-53-6.mol

Synonyms:4-(5-amino-1,3,4-thiadiazol-2-yl)phenol;59565-53-6;4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol;CHEMBL4471826;GVY;Oprea1_052700;SCHEMBL11340093;DTXSID40419970;BDBM50502115;MFCD03659018;STK827891;AKOS000224931;CCG-116760;AS-38721;BB 0253996;CS-0243382;EN300-263140;4-(5-amino-[1,3,4]thiadiazol-2-yl)-phenol, AldrichCPR

Suppliers and Price of 4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol
100mg
$ 200.00

TRC
4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol
50mg
$ 130.00

Matrix Scientific
4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol
500mg
$ 520.00

Matrix Scientific
4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol
1g
$ 800.00

Crysdot
4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol 95+%
1g
$ 589.00

American Custom Chemicals Corporation
4-(5-AMINO-1,3,4-THIADIAZOL-2-YL)PHENOL 95.00%
5MG
$ 497.59

AK Scientific
4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol
500mg
$ 752.00

Total 3 raw suppliers

Chemical Property of 4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol

Chemical Property:

Melting Point:320 °C(Solv: ethanol (64-17-5))
Boiling Point:435.0±47.0 °C(Predicted)
PKA:8.26±0.15(Predicted)
PSA：100.27000
Density:1.471±0.06 g/cm3(Predicted)
LogP:2.07410
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:193.03098303
Heavy Atom Count:13
Complexity:173

Purity/Quality:

98%min ^*data from raw suppliers

4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NN=C(S2)N)O

Technology Process of 4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol

There total 10 articles about 4-(5-Amino-1,3,4-thiadiazol-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 79-19-6
thiosemicarbazide

: 59565-53-6
5-(4-hydroxy phenyl)-1,3,4-thiadiazole-2-amine

Guidance literature:: With tert.-butylhydroperoxide; In ethanol; water; at 20 ℃; for 4h; Green chemistry;
DOI:10.1080/00397911.2017.1398330

Reference yield: 78.0%

: 5339-74-2
4-hydroxybenzaldehyde thiosemicarbazone

: 59565-53-6
5-(4-hydroxy phenyl)-1,3,4-thiadiazole-2-amine

Guidance literature:: With iron(III) chloride; sodium acetate; In acetic acid; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmcl.2011.08.022

Reference yield: 73.0%

: 7001-76-5
4-(2-thiocarbamoylhydrazinocarbonyl) phenyl acetate

: 59565-53-6
5-(4-hydroxy phenyl)-1,3,4-thiadiazole-2-amine

Guidance literature:: 4-(2-thiocarbamoylhydrazinocarbonyl) phenyl acetate; With trichlorophosphate; Reflux;

With water; Reflux;
DOI:10.1016/j.bioorg.2018.06.036