5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid

Base Information

Chemical Name:5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid
CAS No.:120729-93-3
Molecular Formula:C₁₃H₁₆N₂O₄S
Molecular Weight:296.347
Hs Code.:
DSSTox Substance ID:DTXSID70923550
Wikidata:Q82897563

Synonyms:120729-93-3;BRN 3561113;5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid;5-(N,N-Dimethylsulfamoyl)-1-ethyl-1H-indole-3-carboxylic acid;1H-Indole-3-carboxylic acid, 5-((dimethylamino)sulfonyl)-1-ethyl-;5-(Dimethylsulfamoyl)-1-ethyl-1H-indole-3-carboxylic acid;DTXSID70923550;AKOS000112908;CCG-201576;LS-82661

Suppliers and Price of 5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid

Chemical Property:

Vapor Pressure:6.73E-12mmHg at 25°C
Boiling Point:526.1°Cat760mmHg
Flash Point:272°C
Density:1.35g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:296.08307817
Heavy Atom Count:20
Complexity:471

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C2=C1C=CC(=C2)S(=O)(=O)N(C)C)C(=O)O

Technology Process of 5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid

There total 4 articles about 5-((Dimethylamino)sulfonyl)-1-ethyl-1H-indole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.1%

: 120729-89-7
1-Ethyl-3-formyl-1H-indole-5-sulfonic acid dimethylamide

: 120729-93-3
5-Dimethylsulfamoyl-1-ethyl-1H-indole-3-carboxylic acid

Guidance literature:: With potassium permanganate; In water; acetone; at 30 - 35 ℃; for 2h;
DOI:10.1007/BF00764459

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 120729-93-3
5-Dimethylsulfamoyl-1-ethyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 56 percent / chlorosulfonic acid / 2 h / 70 °C

2: 64.2 percent / H₂O; tetrahydrofuran / 30 - 35 °C

3: 54.3 percent

4: 48.1 percent / potassium permanganate / acetone; H₂O / 2 h / 30 - 35 °C

With chlorosulfonic acid; potassium permanganate; In tetrahydrofuran; water; acetone;
DOI:10.1007/BF00764459

Reference yield:

: 120768-89-0
5-chlorosulfonyl-3-formylindole

: 120729-93-3
5-Dimethylsulfamoyl-1-ethyl-1H-indole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 64.2 percent / H₂O; tetrahydrofuran / 30 - 35 °C

2: 54.3 percent

3: 48.1 percent / potassium permanganate / acetone; H₂O / 2 h / 30 - 35 °C

With potassium permanganate; In tetrahydrofuran; water; acetone;
DOI:10.1007/BF00764459