2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl-

Base Information

Chemical Name:2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl-
CAS No.:596122-07-5
Molecular Formula:C21H28O4S
Molecular Weight:376.517
Hs Code.:

Synonyms:

Suppliers and Price of 2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl-

There total 7 articles about 2-Cyclopenten-1-one, 3-ethoxy-5-[(3E)-5-hydroxy-4-methyl-6-(phenylsulfinyl)-3-hexenyl]-5-meth yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1193-82-4
racemic methyl phenyl sulfoxide

: 596109-29-4
5-(4-ethoxy-1-methyl-2-oxocyclopent-3-enyl)-2-methylpent-2-enal

: 596122-07-5
5-(6-benzenesulfinyl-5-hydroxy-4-methylhex-3-enyl)-3-ethoxy-5-methylcyclopent-2-enone

Guidance literature:: racemic methyl phenyl sulfoxide; With n-butyllithium; diisopropylamine; In tetrahydrofuran; at -78 ℃; for 0.5h;

5-(4-ethoxy-1-methyl-2-oxocyclopent-3-enyl)-2-methylpent-2-enal; In tetrahydrofuran; at -78 ℃; for 1h;
DOI:10.1021/jo034280n

Reference yield:

: 22627-70-9
3-ethoxycyclopent-2-en-1-one

: 596122-07-5
5-(6-benzenesulfinyl-5-hydroxy-4-methylhex-3-enyl)-3-ethoxy-5-methylcyclopent-2-enone

Guidance literature:: Multi-step reaction with 7 steps

1.1: n-BuLi; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C

1.2: 60 percent / tetrahydrofuran / 3 h / -78 °C

2.1: KH / dimethylformamide / 0.17 h / 20 °C

2.2: 77 percent / dimethylformamide / 3 h

3.1: 74 percent / KOH / ethanol / 16 h / Heating

4.1: n-BuLi; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C

4.2: 81 percent / tetrahydrofuran / 3 h / -78 °C

5.1: Sudan Red 23; ozone / CH₂Cl₂; methanol / 0.08 h / -78 °C

5.2: 90 percent / PPh₃ / CH₂Cl₂; methanol / -78 - 20 °C

6.1: 293 mg / benzene / 10 h / Heating

7.1: n-BuLi; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C

7.2: 55 percent / tetrahydrofuran / 1 h / -78 °C

With potassium hydroxide; n-butyllithium; potassium hydride; ozone; diisopropylamine; Sudan III; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; benzene; 6.1: Wittig reaction;
DOI:10.1021/jo034280n

Reference yield:

: 596109-24-9
4-ethoxy-2-oxocyclopent-3-enecarboxylic acid methyl ester

: 596122-07-5
5-(6-benzenesulfinyl-5-hydroxy-4-methylhex-3-enyl)-3-ethoxy-5-methylcyclopent-2-enone

Guidance literature:: Multi-step reaction with 6 steps

1.1: KH / dimethylformamide / 0.17 h / 20 °C

1.2: 77 percent / dimethylformamide / 3 h

2.1: 74 percent / KOH / ethanol / 16 h / Heating

3.1: n-BuLi; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C

3.2: 81 percent / tetrahydrofuran / 3 h / -78 °C

4.1: Sudan Red 23; ozone / CH₂Cl₂; methanol / 0.08 h / -78 °C

4.2: 90 percent / PPh₃ / CH₂Cl₂; methanol / -78 - 20 °C

5.1: 293 mg / benzene / 10 h / Heating

6.1: n-BuLi; diisopropylamine / tetrahydrofuran / 0.5 h / -78 °C

6.2: 55 percent / tetrahydrofuran / 1 h / -78 °C

With potassium hydroxide; n-butyllithium; potassium hydride; ozone; diisopropylamine; Sudan III; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; benzene; 5.1: Wittig reaction;
DOI:10.1021/jo034280n