1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-

Base Information

Chemical Name:1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-
CAS No.:86523-91-3
Molecular Formula:C18H23N5O
Molecular Weight:325.414
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00235633
Wikidata:Q83117514
ChEMBL ID:CHEMBL56300
Mol file:86523-91-3.mol

Synonyms:BRN 5622488;1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-;86523-91-3;N-(2-Aminophenyl)-4-(2-pyridinyl)-1-piperazinepropanamide;CHEMBL56300;DTXSID00235633;LS-113165

Suppliers and Price of 1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-PIPERAZINEPROPANAMIDE, N-(2-AMINOPHENYL)-4-(2-PYRIDINYL)- 95.00%
5MG
$ 502.91

Total 3 raw suppliers

Chemical Property of 1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-

Chemical Property:

Vapor Pressure:6.86E-14mmHg at 25°C
Melting Point:149-150 °C
Boiling Point:589.9°Cat760mmHg
PKA:14.48±0.70(Predicted)
Flash Point:310.5°C
PSA：77.98000
Density:1.235g/cm³
LogP:3.04820
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:325.19026037
Heavy Atom Count:24
Complexity:397

Purity/Quality:: 1-PIPERAZINEPROPANAMIDE, N-(2-AMINOPHENYL)-4-(2-PYRIDINYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(=O)NC2=CC=CC=C2N)C3=CC=CC=N3

Technology Process of 1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)-

There total 3 articles about 1-Piperazinepropanamide, N-(2-aminophenyl)-4-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 86523-97-9
N-(2-Nitro-phenyl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

: 86523-91-3
N-(2-Amino-phenyl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 3102.9 Torr;
DOI:10.1021/jm00384a002

Reference yield:

: 34803-66-2
1-(2-pyridyl)piperazine

: 86523-91-3
N-(2-Amino-phenyl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / toluene / Heating

2: 68 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

With hydrogen; palladium on activated charcoal; In methanol; toluene;
DOI:10.1021/jm00384a002

Reference yield:

: 104373-98-0
N-(2-nitrophenyl)prop-2-enamide

: 86523-91-3
N-(2-Amino-phenyl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / toluene / Heating

2: 68 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

With hydrogen; palladium on activated charcoal; In methanol; toluene;
DOI:10.1021/jm00384a002