21-oxoisopteropodine

Base Information

• Chemical Name: 21-oxoisopteropodine
• CAS No.: 131724-59-9
• Molecular Formula: C₂₁H₂₂N₂O₅
• Molecular Weight: 382.416
• Mol file: 131724-59-9.mol

Synonyms:Formosanan-16-carboxylicacid, 19-methyl-2,21-dioxo-, methyl ester, (3b,15b,19b)-(?à)-;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid,1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2,10'-dioxo-, methyl ester, (1'a,4'aa,5'aa,6'a,10'aa)- (9CI)

Chemical Property of 21-oxoisopteropodine

Chemical Property:

• Vapor Pressure: 2.63E-15mmHg at 25°C
• Boiling Point: 620.2°Cat760mmHg
• Flash Point: 328.9°C
• Density: 1.4g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 21-oxoisopteropodine

There total 4 articles about 21-oxoisopteropodine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(7aR,8S,11aS,12aS)-8-Methyl-7-oxo-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester (116005-85-7,134001-72-2) → C21H22N2O5 (82564-37-2,131724-59-9,134002-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: t-BuOCl, Et₃N

2: AgClO₄, HClO₄ / methanol; H₂O

With perchloric acid; tert-butylhypochlorite; silver perchlorate; triethylamine; In methanol; water;

DOI:10.1016/S0040-4039(00)97675-5

Reference yield:

(7aR,8S,11aS,12aS)-8-Methyl-7-oxo-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester (116005-85-7,134001-72-2) → C21H22N2O5 (82564-37-2,131724-59-9,134002-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: t-BuOCl, Et₃N

2: AgClO₄, HClO₄ / methanol; H₂O

With perchloric acid; tert-butylhypochlorite; silver perchlorate; triethylamine; In methanol; water;

DOI:10.1016/S0040-4039(00)97675-5

Reference yield:

(7aR,8S,11aS,12aS)-4b-Chloro-8-methyl-7-oxo-4b,5,6,7a,8,11a,12,12a-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester → C21H22N2O5 (82564-37-2,131724-59-9,134002-29-2) + C21H22N2O5 (82564-37-2,131724-59-9,134002-29-2)

Guidance literature:

With perchloric acid; silver perchlorate; In methanol; water; Yield given;

DOI:10.1016/S0040-4039(00)97675-5

upstream raw materials:

(7aR,8S,11aS,12aS)-8-Methyl-7-oxo-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester

Downstream raw materials:

isopteropodine

Refernces