8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid

Base Information

Chemical Name:8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid
CAS No.:59784-54-2
Molecular Formula:C21H29FO5
Molecular Weight:380.457
Hs Code.:
DSSTox Substance ID:DTXSID701188004

Synonyms:DTXSID701188004;8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid;59784-54-2

Suppliers and Price of 8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:14
Exact Mass:380.19990218
Heavy Atom Count:27
Complexity:458

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C(CCCC(COC1=CC=C(C=C1)F)O)CC=CCCCC(=O)O

Technology Process of 8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid

There total 4 articles about 8-Acetyl-13-(4-fluorophenoxy)-12-hydroxy-5-tridecenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63247-34-7
8-acetyl-12-hydroxy-13-(4-fluorophenoxy)-5-tridecynoic acid

: 59784-54-2
(Z)-8-Acetyl-13-(4-fluoro-phenoxy)-12-hydroxy-tridec-5-enoic acid

Guidance literature:: With hydrogen; Lindlar's catalyst; In ethyl acetate;
DOI:10.1021/jm00208a003

Reference yield:

: 63247-33-6
methyl 8-ethoxycarbonyl-9-oxo-5-decynoate

: 59784-54-2
(Z)-8-Acetyl-13-(4-fluoro-phenoxy)-12-hydroxy-tridec-5-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NaH, benzene, DMF, (ii) /BRN= 2057733/, (iii) aq. NaOH, MeOH

2: H₂ / Lindlar catalyst / ethyl acetate

With hydrogen; Lindlar's catalyst; In ethyl acetate;
DOI:10.1021/jm00208a003

Reference yield:

: 41349-38-6
methyl 7-bromohept-5-ynoate

: 59784-54-2
(Z)-8-Acetyl-13-(4-fluoro-phenoxy)-12-hydroxy-tridec-5-enoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaH, benzene, DMF, (ii) /BRN= 970685/

2: (i) NaH, benzene, DMF, (ii) /BRN= 2057733/, (iii) aq. NaOH, MeOH

3: H₂ / Lindlar catalyst / ethyl acetate

With hydrogen; Lindlar's catalyst; In ethyl acetate;
DOI:10.1021/jm00208a003