exo-3-(Boc-aMino)-9-azabi...

Base Information

• Chemical Name: exo-3-(Boc-aMino)-9-azabi...
• CAS No.: 599165-35-2
• Molecular Formula: C13H24N2O2
• Molecular Weight: 240.34200
• Mol file: 599165-35-2.mol

Synonyms:

Chemical Property of exo-3-(Boc-aMino)-9-azabi...

Chemical Property:

• Boiling Point: 356.5±31.0 °C(Predicted)
• PKA: 12.40±0.40(Predicted)
• PSA: 53.85000
• Density: 1.06±0.1 g/cm3(Predicted)
• LogP: 2.71740

Purity/Quality:

NLT 98% ^*data from raw suppliers

Exo-3-(boc-amino)-9-azabicyclo[3.3.1]nonane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of exo-3-(Boc-aMino)-9-azabi...

There total 11 articles about exo-3-(Boc-aMino)-9-azabi... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C20H30N2O2 → C13H24N2O2 (599165-35-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; ethyl acetate;

DOI:10.1016/j.tetlet.2019.150994

Reference yield: 89.0%

tert-butyl 9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamate (1006601-11-1) → tert-butyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamate (155560-04-6,1208530-70-4,599165-35-2)

Guidance literature:

With sodium hydroxide; potassium permanganate; water; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

3α-<(tert-butyloxycarbonyl)amino>-9-benzyl-9-azabicyclo<3.3.1>nonane → tert-butyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamate (155560-04-6,1208530-70-4,599165-35-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; acetic acid; In ethanol; ethyl acetate; at 40 - 50 ℃; under 760.051 Torr;

DOI:10.1039/c3ob40489g

upstream raw materials:

tert-butyl 9-methyl-9-azabicyclo[3.3.1]nonan-3-ylcarbamate

Glutaraldehyde

(±)-(1R,3r,5S)-9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl acetate

Refernces

• 1、 Frantz, Marie-Céline,Skoda, Erin M.,Sacher, Joshua R.,Epperly, Michael W.,Goff, Julie P.,Greenberger, Joel S.,Wipf, Peter. "Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria". . p. 4147 - 4153. Retrieved 2013/07/19.