Oosponol

Base Information

• Chemical Name: Oosponol
• CAS No.: 146-04-3
• Molecular Formula: C₁₁H₈O₅
• Molecular Weight: 220.182
• UNII: SJ73CZU3LE
• DSSTox Substance ID: DTXSID80163248
• Nikkaji Number: J71.270A
• Wikidata: Q83032137
• Metabolomics Workbench ID: 100346
• Mol file: 146-04-3.mol

Synonyms:oosponol

Chemical Property of Oosponol

Chemical Property:

• Vapor Pressure: 2.96E-10mmHg at 25°C
• Boiling Point: 485.9°Cat760mmHg
• Flash Point: 198.9°C
• PSA: 87.74000
• Density: 1.547g/cm³
• LogP: 0.67360
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 220.03717335
• Heavy Atom Count: 16
• Complexity: 346

Purity/Quality:

98%min ^*data from raw suppliers

OOSPONOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)O)C(=O)OC=C2C(=O)CO

Technology Process of Oosponol

There total 4 articles about Oosponol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Acetic acid 2-(8-hydroxy-1-oxo-1H-isochromen-4-yl)-2-oxo-ethyl ester → oosponol (146-04-3)

Guidance literature:

With phosphate buffer; In dichloromethane; for 8h; Ambient temperature; Pseudomonas fluorescence lipase (3592 U);

DOI:10.1002/jlac.199719970130

Reference yield:

oospoglycol → oosponol (146-04-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 62 percent / CH₂Cl₂ / 20 h / Ambient temperature; Pseudomonas fluorescens lipase (4490 U)

2: 39 percent / aq. CrO₃, 98percent H₂SO₄ / acetone / 0.5 h / Ambient temperature

3: 95 percent / phosphate buffer (pH 5) / CH₂Cl₂ / 8 h / Ambient temperature; Pseudomonas fluorescence lipase (3592 U)

With chromium(VI) oxide; phosphate buffer; sulfuric acid; In dichloromethane; acetone;

DOI:10.1002/jlac.199719970130

Reference yield:

Acetic acid 2-hydroxy-2-(8-hydroxy-1-oxo-1H-isochromen-4-yl)-ethyl ester → oosponol (146-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 39 percent / aq. CrO₃, 98percent H₂SO₄ / acetone / 0.5 h / Ambient temperature

2: 95 percent / phosphate buffer (pH 5) / CH₂Cl₂ / 8 h / Ambient temperature; Pseudomonas fluorescence lipase (3592 U)

With chromium(VI) oxide; phosphate buffer; sulfuric acid; In dichloromethane; acetone;

DOI:10.1002/jlac.199719970130