4-Chloro-4'-iodobiphenyl

Base Information

• Chemical Name: 4-Chloro-4'-iodobiphenyl
• CAS No.: 60200-91-1
• Molecular Formula: C12H8ClI
• Molecular Weight: 314.553
• Hs Code.: 2903998090
• Mol file: 60200-91-1.mol

Synonyms:Methanone,(4-chlorophenyl)(4-iodophenyl);4-Chlor-4'-jod-biphenyl;4'-Jod-4-chlor-biphenyl;4-(4-chlorophenyl)iodobenzene;(4-chloro-phenyl)-(4-iodo-phenyl)-methanone;4-chloro-4'-iodobiphenyle;4-chloro-4'-iodo-biphenyl;4-Chlor-4'-jod-benzophenon;4-chloro-4'-iodo-benzophenone;

Chemical Property of 4-Chloro-4'-iodobiphenyl

Chemical Property:

• PSA: 0.00000
• LogP: 4.61160

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-4'-iodobiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chloro-4'-iodobiphenyl

There total 17 articles about 4-Chloro-4'-iodobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.55%

4-iodo-biphenyl (1591-31-7) → 4-chloro-4'-iodo-1,1'-biphenyl (60200-91-1)

Guidance literature:

With sulfuryl dichloride; diphenyl sulfide; antimony(III) chloride; In 1,2-dichloro-ethane; at 20 - 25 ℃; for 5h;

Reference yield: 78.0%

(4'-chloro-biphenyl-4-yl)-trimethyl-silane (17908-92-8) → 4-chloro-4'-iodo-1,1'-biphenyl (60200-91-1)

Guidance literature:

With Iodine monochloride; In dichloromethane; at -50 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/adsc.202000306

Reference yield: 74.0%

4'-biphenyl chloride (2051-62-9,80333-62-6) → 4-chloro-4'-iodo-1,1'-biphenyl (60200-91-1)

Guidance literature:

With sulfuric acid; iodine; nitric acid; acetic acid; at 35 - 40 ℃; for 18h;

DOI:10.1021/jm901300d

upstream raw materials:

4-(4-chlorophenyl)aniline

iodobenzene

1,6-bis-(4-chlorophenyl)-3,4-diacetyl-1,5-hexazadiene

4'-biphenyl chloride

Downstream raw materials:

2-(4'-chloro-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4'-biphenyl chloride