2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile

Base Information

Chemical Name:2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile
CAS No.:6958-33-4
Molecular Formula:C₁₈H₂₁N₃O₇
Molecular Weight:391.381
Hs Code.:

Synonyms:Malonicacid, acetamido[(5-nitroindol-3-yl)methyl]-, diethyl ester (6CI,8CI);Propanedioic acid, (acetylamino)[(5-nitro-1H-indol-3-yl)methyl]-, diethyl ester(9CI); NSC 64692; NSC 78038

Suppliers and Price of 2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile

Chemical Property:

Vapor Pressure:1.88E-14mmHg at 25°C
Boiling Point:615.8°Cat760mmHg
Flash Point:326.2°C
Density:1.342g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile

There total 3 articles about 2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 3414-64-0
N,N-dimethyl-5-nitro-1H-indole-3-methanamine

: 1068-90-2
2-acetylaminomalonic acid diethyl ester

: 6958-33-4
diethyl acetylamino<(5-nitroindol)-3-ylmethyl>malonate

Guidance literature:: With sodium hydroxide; In toluene; at 110 ℃; Inert atmosphere;
DOI:10.1039/c7ob02529g

Reference yield:

: 6146-52-7
5-nitroindole

: 6958-33-4
diethyl acetylamino<(5-nitroindol)-3-ylmethyl>malonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / 0.5 h / 0 °C

1.2: 72 h / 20 °C

1.3: 0 °C / pH 13

2.1: sodium hydroxide / toluene / 110 °C / Inert atmosphere

With acetic acid; sodium hydroxide; In toluene;
DOI:10.1039/c7ob02529g