4-Ethoxycarbonyl-2-methoxyphenylboronic acid

Base Information

• Chemical Name: 4-Ethoxycarbonyl-2-methoxyphenylboronic acid
• CAS No.: 603122-86-7
• Molecular Formula: C10H13BO5
• Molecular Weight: 224.021
• Mol file: 603122-86-7.mol

Synonyms:4-ETHOXYCARBONYL-2-METHOXYPHENYLBORONIC ACID;

Chemical Property of 4-Ethoxycarbonyl-2-methoxyphenylboronic acid

Chemical Property:

• PSA: 75.99000
• LogP: -0.44830

Purity/Quality:

99% ^*data from raw suppliers

(4-(Ethoxycarbonyl)-2-methoxyphenyl)boronicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Ethoxycarbonyl-2-methoxyphenylboronic acid

There total 2 articles about 4-Ethoxycarbonyl-2-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-methoxy-4-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate → [4-(ethoxycarbonyl)-2-methoxyphenyl]boronic acid (603122-86-7)

Guidance literature:

With sodium periodate; water; In tetrahydrofuran; at 20 ℃; for 2.16667h;

Reference yield:

→ [4-(ethoxycarbonyl)-2-methoxyphenyl]boronic acid (603122-86-7)

Guidance literature:

Reference yield:

[4-(ethoxycarbonyl)-2-methoxyphenyl]boronic acid (603122-86-7) → 4-(dihydroxyboranyl)-3-methoxybenzoic acid

Guidance literature:

[4-(ethoxycarbonyl)-2-methoxyphenyl]boronic acid; With lithium hydroxide; water; In 1,4-dioxane; at 20 ℃;

With hydrogenchloride; In 1,4-dioxane; water;

Downstream raw materials:

ethyl 4'-[2-[(tert-butoxycarbonyl)[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]-amino]ethyl]-2-methoxy-1,1'-biphenyl-4-carboxylate

Refernces

• 1、 -. "AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF". Page/Page column 29. . Retrieved 2008/06/13.