2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine

Base Information

Chemical Name:2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine
CAS No.:60372-08-9
Molecular Formula:C₁₆H₁₉NO₃
Molecular Weight:273.332
Hs Code.:
DSSTox Substance ID:DTXSID80571561
Mol file:60372-08-9.mol

Synonyms:60372-08-9;2-amino-1-(3-methoxy-4-phenylmethoxyphenyl)ethanol;2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine;2-Amino-1-[4-(benzyloxy)-3-methoxyphenyl]ethan-1-ol;alpha-(AMinoMethyl)-3-Methoxy-4-(phenylMethoxy)-benzeneMethanol;DTXSID80571561

Suppliers and Price of 2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine
100mg
$ 195.00

Medical Isotopes, Inc.
2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine
1 g
$ 2400.00

Total 3 raw suppliers

Chemical Property of 2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine

Chemical Property:

PSA：64.71000
LogP:2.96660
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:273.13649347
Heavy Atom Count:20
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)C(CN)O)OCC2=CC=CC=C2
Uses α-(AMinoMethyl)-3-Methoxy-4-(phenylMethoxy)-benzeneMethanol is used in the preparation of Sevanine.

Technology Process of 2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine

There total 4 articles about 2-(4-Benzyloxy-2-methoxyphenyl)-2-hydroxy-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: (4-Benzyloxy-3-methoxy-phenyl)-trimethylsilanyloxy-acetonitrile

: 60372-08-9
2-Amino-1-(4-benzyloxy-3-methoxy-phenyl)-ethanol

Guidance literature:: With B₂H₆-THF;
DOI:10.1080/00397919808007179

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 60372-08-9
2-Amino-1-(4-benzyloxy-3-methoxy-phenyl)-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / montmorillonite-K₁₀ / diethyl ether / 1 h / 0 °C

2: 40 percent / B₂H₆*THF

With B₂H₆-THF; Montmorillonite-K₁₀; In diethyl ether;
DOI:10.1080/00397919808007179