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2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester, (2Z)-

Base Information
  • Chemical Name:2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester, (2Z)-
  • CAS No.:603998-99-8
  • Molecular Formula:C14H16F3NO2
  • Molecular Weight:287.282
  • Hs Code.:
2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester,
(2Z)-

Synonyms:

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Chemical Property of 2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester, (2Z)-
Chemical Property:
Purity/Quality:
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Technology Process of 2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester, (2Z)-

There total 1 articles about 2-Pentenoic acid, 3-amino-5-[4-(trifluoromethyl)phenyl]-, ethyl ester, (2Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With ammonium acetate; In benzene; for 2h; Heating / reflux;
Guidance literature:
C12H18NO5Pol; 4-nitro-benzoic acid; With piperidine; trimethyl orthoformate; In DMF (N,N-dimethyl-formamide); at 65 ℃; for 18h;
ethyl (2Z)-3-amino-5-(4-(trifluoromethyl)phenyl)-2-pentenoate; With trimethyl orthoformate; In DMF (N,N-dimethyl-formamide); at 80 ℃; for 16h;
With triethylamine; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; tin(ll) chloride; more than 3 stages;
Guidance literature:
4-formyl-N-furan-2-ylmethyl-benzenesulfonamide; C12H18NO5Pol; With piperidine; acetic acid; trimethyl orthoformate; In DMF (N,N-dimethyl-formamide); at 65 ℃; for 14h;
ethyl (2Z)-3-amino-5-(4-(trifluoromethyl)phenyl)-2-pentenoate; With trimethyl orthoformate; In DMF (N,N-dimethyl-formamide); at 80 ℃; for 16h;
With methyl-phenyl-thioether; triethylamine; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; phenol; more than 3 stages;
upstream raw materials:

ethyl 3-oxo-5-(4-trifluoromethylphenyl)pentanoate

Downstream raw materials:

C36H41F3N2O8

C42H44F3N3O8S

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